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Temporomandibular joint (TMJ) arthritis impacts mandibular growth and development. This can result in skeletal deformity, such as facial asymmetry and/or malocclusion asymmetry. This article reviews the unique properties of TMJ and dentofacial growth and development in the setting of juvenile idiopathic arthritis (JIA). Specific orthopedic/orthodontic and surgical management of children with JIA and TMJ arthritis is discussed. The importance of interdisciplinary collaboration is highlighted.
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http://dx.doi.org/10.1016/j.coms.2019.09.002 | DOI Listing |
Front Pediatr
August 2025
Department of Pediatrics, Shengjing Hospital of China Medical University, Shenyang, China.
Objective: To describe the efficacy and safety of tofacitinib for pediatric Still's disease, also referred to as systemic-onset juvenile idiopathic arthritis (sJIA). Traditional non-biological drugs and drugs targeting the interleukin-1 and interleukin-6 pathways benefit some patients, but others show inadequate responses.
Methods: We retrospectively analyzed ten patients with pediatric Still's disease who were treated with tofacitinib and had at least one follow-up visit.
Int J Rheum Dis
September 2025
Department of Pediatrics, Facultad de Medicina, Universidad Nacional de Asunción, Asunción, Paraguay.
Introduction: Vitamin D plays a crucial role in modulating the immune system. Numerous studies have elucidated the association between low serum levels of vitamin D and autoimmune diseases. Vitamin D deficiency has been implicated in systemic lupus erythematosus, rheumatoid arthritis (RA), Hashimoto's thyroiditis, juvenile dermatomyositis, inflammatory bowel disease, among others.
View Article and Find Full Text PDFIntractable Rare Dis Res
August 2025
Division of Pharmacy Practice and Administrative Sciences, James L. Winkle College of Pharmacy, University of Cincinnati Academic Health Center, Cincinnati, Ohio, USA.
Juvenile idiopathic arthritis (JIA) is the most common rheumatological disease in children. Besides the more severe systemic form, non-systemic JIA is divided into 5 different subgroups. Polyarticular JIA (polyJIA), particularly rheumatoid factor (RF)-positive, which is defined as the disease involving five or more joints in the first 6 months of disease, has the worst prognosis.
View Article and Find Full Text PDFSemin Arthritis Rheum
August 2025
Division of Rheumatology, Department of Medicine, Solna, Karolinska Institutet, Stockholm, Sweden; Department of Gastroenterology, Dermatology and Rheumatology, Theme Inflammation and Aging, Karolinska University Hospital, Stockholm, Sweden. Electronic address:
Objective: A revision of the 2017 EULAR-ACR myositis classification criteria, namely EULAR-ACR funded Myositis Revision of Classification (MyoROC) project, is currently underway involving a large international group of experts. In the first phase of this project, we identified additional items to be tested in the criteria.
Methods: We distributed an electronic survey to International Myositis Assessment and Clinical Studies (IMACS) members to identify new items.
Ann Med Surg (Lond)
September 2025
Saint Agnes Medical Center, Fresno, California, USA.
Background: Systemic juvenile idiopathic arthritis (SJIA) is a unique subtype of juvenile idiopathic arthritis (JIA) with very special clinical manifestations, complications, and management options. The simultaneous presentation of tinea capitis and eosinophilia has not been reported in the context of Systemic Juvenile Idiopathic Arthritis before.
Case Presentation: A 5-year-old Sudanese boy presented with fever and bilateral ankle arthritis in a background of extensive scalp lesions, which were scaly, itchy, and associated with hair loss.