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http://dx.doi.org/10.1186/s12859-019-3133-6 | DOI Listing |
IEEE Trans Med Imaging
August 2025
Pixel-to-pixel variation in outputs of photon-counting detectors (PCDs) is a significant challenge in computed tomography (CT) imaging, leading to ring artifacts. This study presents a novel calibration framework to address this issue. Our approach involves a streamlined data acquisition strategy using CT scans of calibration phantoms, enabling comprehensive phantom thickness data acquisition across all pixels, coupled with three dedicated calibration steps.
View Article and Find Full Text PDFMed Phys
July 2025
Department of Oncology, KU Leuven, Leuven, Belgium.
Background: Patient-Specific Quality Assurance in Radiotherapy (PSQA) demands high-resolution dosimetry to verify accurate dose delivery in personalized intensity-modulated radiotherapy (IMRT) and volumetric-modulated arc therapy (VMAT) treatments. A novel optically stimulated luminescence (OSL) film dosimeter made with BaFBr:Eu phosphor, offers submm spatial resolution. However, its energy-dependent response, requires corrections.
View Article and Find Full Text PDFRev Sci Instrum
April 2025
Department of Chemistry and Biochemistry, Georgia Institute of Technology, 950 Atlantic Drive, Atlanta, Georgia 30332, USA.
Broadband coherent anti-Stokes Raman scattering (BCARS) microscopy is a label-free imaging approach that provides detailed chemical information at high spatial resolution in a sample through nonlinear, coherent excitation of molecular vibrations and detection of Raman spectra. While its utility for biological imaging has been demonstrated, many aspects of this technique must mature before it can be widely adopted. One of the areas of required improvement is imaging speed-most BCARS implementations involve sample rastering, which limits imaging speed.
View Article and Find Full Text PDFComput Med Imaging Graph
April 2025
Department of Health Technology and Informatics, The Hong Kong Polytechnic University, 999077, Hong Kong SAR; Research Institute for Intelligent Wearable Systems, The Hong Kong Polytechnic University, 999077, Hong Kong SAR; The Hong Kong Polytechnic University Shenzhen Research Institute, Shenzhen,
Thoracic Cone-beam computed tomography (CBCT) is routinely collected during image-guided radiation therapy (IGRT) to provide updated patient anatomy information for lung cancer treatments. However, CBCT images often suffer from streaking artifacts and noise caused by under-rate sampling projections and low-dose exposure, resulting in loss of lung anatomy which contains crucial pulmonary tumorous and functional information. While recent deep learning-based CBCT enhancement methods have shown promising results in suppressing artifacts, they have limited performance on preserving anatomical details containing crucial tumorous information due to lack of targeted guidance.
View Article and Find Full Text PDFSensors (Basel)
December 2022
Institute for Computer Science and Control (SZTAKI), Eötvös Loránd Research Network (ELKH), Kende u. 13-17, 1111 Budapest, Hungary.
Flat-field correction (FFC) is commonly used in image signal processing (ISP) to improve the uniformity of image sensor pixels. Image sensor nonuniformity and lens system characteristics have been known to be temperature-dependent. Some machine vision applications, such as visual odometry and single-pixel airborne object tracking, are extremely sensitive to pixel-to-pixel sensitivity variations.
View Article and Find Full Text PDF