Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Recently, a novel plasmid-mediated tigecycline resistance mechanism, Tet(X4), has raised a global antimicrobial resistance concern (1, 2).….
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6879257 | PMC |
| http://dx.doi.org/10.1128/AAC.01528-19 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
The systematic assessment of completeness of public metadata accompanying omics studies in the Gene Expression Omnibus data repository.
Genome Biol
September 2025
Department of Clinical Pharmacy, Alfred E. Mann School of Pharmacy and Pharmaceutical Sciences, University of Southern California, Los Angeles, CA, 90089, USA.
Background: Recent advances in high-throughput sequencing technologies have enabled the collection and sharing of a massive amount of omics data, along with its associated metadata-descriptive information that contextualizes the data, including phenotypic traits and experimental design. Enhancing metadata availability is critical to ensure data reusability and reproducibility and to facilitate novel biomedical discoveries through effective data reuse. Yet, incomplete metadata accompanying public omics data may hinder reproducibility and reusability and limit secondary analyses.
View Article and Find Full Text PDFDistinct evolutionary trajectories of subgenomic centromeres in polyploid wheat.
Genome Biol
September 2025
Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, 100101, Beijing, China.
Background: Centromeres are crucial for precise chromosome segregation and maintaining genome stability during cell division. However, their evolutionary dynamics, particularly in polyploid organisms with complex genomic architectures, remain largely enigmatic. Allopolyploid wheat, with its well-defined hierarchical ploidy series and recent polyploidization history, serves as an excellent model to explore centromere evolution.
View Article and Find Full Text PDFDengue virus infection reprograms baseline innate immune gene expression.
Med
September 2025
Viral Research and Experimental Medicine Centre, SingHealth Duke-NUS Academic Medical Centre, Singapore 169856, Singapore; Program in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore 169857, Singapore; Department of Clinical Translational Research, Singapore General Hospital, Singapo
Background: All three dengue vaccines that have completed phase 3 clinical trials have shown greater efficacy in dengue-seropositive compared to dengue-seronegative individuals. This includes the live-attenuated tetravalent dengue vaccine TAK-003, where immunogenicity in baseline seronegative individuals remains lower after two doses, despite seroconversion after the first dose, compared to baseline seropositive individuals after one dose.
Methods: A whole-genome microarray was used to analyze the host response to TAK-003.
Rickettsia lanei, sp. nov. (Rickettsiales: Rickettsiaceae), a Newly Recognized Pathogen of Humans Associated with the Rabbit Tick, Haemaphysalis leporispalustris (Acari: Ixodidae).
Am J Trop Med Hyg
September 2025
Rickettsial Zoonoses Branch, Centers for Disease Control and Prevention, Atlanta, Georgia.
Haemaphysalis leporispalustris (the rabbit tick) is one of the most broadly distributed hard tick species in the Americas. In 2018, investigators amplified DNA from a spotted fever group Rickettsia (SFGR) species found in host-seeking larvae and nymphs of H. leporispalustris collected in northern California and proposed the name Candidatus "Rickettsia lanei" using results obtained via multilocus sequence typing.
View Article and Find Full Text PDFExploring the olfactory repertoire of the ecologically important parasitoid wasp Microplitis mediator (Hymenoptera: Braconidae): from gene structures to expression analysis.
J Econ Entomol
September 2025
State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing 100193, China.
The ability of parasitoid wasps to precisely locate hosts in complex environments is a key factor in suppressing pest populations. Chemical communication plays an essential role in mediating insect behaviors such as locating food sources, hosts, and mates. Odorant receptors (ORs) are the key connection between external odors and olfactory nerves.
View Article and Find Full Text PDF