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http://dx.doi.org/10.1093/eurheartj/ehz664 | DOI Listing |
Zhong Nan Da Xue Xue Bao Yi Xue Ban
May 2025
Department of Rehabilitation Medicine, Second Xiangya Hospital, Central South University, Changsha 410011.
Objectives: Osteoarthritis (OA) is one of the most common chronic degenerative diseases, with chondrocyte apoptosis and extracellular matrix (ECM) degradation as the major pathological changes. The mechanical stimulation can attenuate chondrocyte apoptosis and promote ECM synthesis, but the underlying molecular mechanisms remain unclear. This study aims to investigate the role of primary cilia (PC) in mediating the effects of mechanical stimulation on OA progression.
View Article and Find Full Text PDFJ Epidemiol
September 2025
Faculty of Sport Sciences, Waseda University.
Background: Brief measures of 24-hour movement behaviors are needed to easily evaluate their durations. The present study investigated the criterion validity and test-retest reliability of a brief self-report instrument to assess 24-hour movement behaviors.
Methods: A paper-based self-administered questionnaire was used to assess sleep, sedentary behavior (SB), light-intensity physical activity (LPA), and moderate-to-vigorous physical activity (MVPA) with four items in 35 healthy adults.
Arch Phys Med Rehabil
September 2025
Department of Physical Therapy, University of Delaware, Newark, DE, USA; Biomechanics and Movement Science Program, University of Delaware, Newark, DE, USA. Electronic address:
Objective: To examine if exercise intensity, quantified as heart rate or training speed, predicts walking outcomes in people with chronic stroke.
Design: This is a secondary analysis from a larger randomized clinical trial ("PROWALKS"; NIH1R01HD086362).
Setting: Four, outpatient rehabilitation clinics.
Psychol Sport Exerc
September 2025
Department of Psychology, The University of Texas at San Antonio, San Antonio, TX, USA.
Identity is among the most robust psychological constructs for predicting whether individuals translate physical activity (PA) intentions into action. However, existing identity measures in the PA domain focus narrowly on exercise and largely adopt limited unidimensional conceptualizations. This study aimed to develop and validate the Multidimensional Inventory of Physical Activity Identity (MIPAI-25), a novel instrument grounded in a multidimensional, theoretically integrated framework.
View Article and Find Full Text PDFJ Physiol
September 2025
Institue for Exercise and Environmental Medicine, Texas Presbyterian Hospital, Dallas, TX, USA.
Some patients with heart failure with preserved ejection fraction (HFpEF) have demonstrated evidence of exercise-induced arterial hypoxaemia (EIAH). However, EIAH was not quantified using , , and measurements as previously conducted in healthy adults nor was EIAH quantified alongside simultaneous measurements of pulmonary vascular pressures, cardiorespiratory responses, or dyspnoea on exertion (DOE) in these patients. Given the effects of hypoxaemia on pulmonary vasoconstriction, cardiorespiratory responses, and DOE, we tested the hypothesis that patients with HFpEF and EIAH (EIAH) would demonstrate higher pulmonary vascular pressures, worse oxygen uptake, and greater DOE compared with patients without EIAH (EIAH).
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