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Background: Anxiety disorder, one of the highly disabling, prevalent and common mental disorders, is known to be more prevalent in persons with type 2 diabetes mellitus (T2DM) than the general population, and the comorbid presence of anxiety disorders is known to have an impact on the diabetes outcome and the quality of life. However, the information on the type of anxiety disorder and its prevalence in persons with T2DM is limited.
Aims: To assess the prevalence and correlates of anxiety disorder in people with type 2 diabetes in different countries.
Methods: People aged 18-65 years with diabetes and treated in outpatient settings were recruited in 15 countries and underwent a psychiatric interview with the Mini-International Neuropsychiatric Interview. Demographic and medical record data were collected.
Results: A total of 3170 people with type 2 diabetes (56.2% women; with mean (SD) duration of diabetes 10.01 (7.0) years) participated. The overall prevalence of anxiety disorders in type 2 diabetic persons was 18%; however, 2.8% of the study population had more than one type of anxiety disorder. The most prevalent anxiety disorders were generalised anxiety disorder (8.1%) and panic disorder (5.1%). Female gender, presence of diabetic complications, longer duration of diabetes and poorer glycaemic control (HbA1c levels) were significantly associated with comorbid anxiety disorder. A higher prevalence of anxiety disorders was observed in Ukraine, Saudi Arabia and Argentina with a lower prevalence in Bangladesh and India.
Conclusions: Our international study shows that people with type 2 diabetes have a high prevalence of anxiety disorders, especially women, those with diabetic complications, those with a longer duration of diabetes and poorer glycaemic control. Early identification and appropriate timely care of psychiatric problems of people with type 2 diabetes is warranted.
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http://dx.doi.org/10.1136/gpsych-2019-100076 | DOI Listing |
Int J Soc Psychiatry
September 2025
Department of Psychology at the Institute of Psychiatry, Psychology, and Neuroscience, King's College London, UK.
Background: Despite growing rates of common mental health disorders among country members of the Association of Southeast Asia Nations (ASEAN), there continue to be treatment gaps in these countries.
Aim: To systematically identify and synthesise barriers and facilitators to accessing formal psychological help for common mental health disorders in the existing literature.
Methods: APA PsycINFO, Web of Science, Scopus, and the Indonesian Portal Garuda were searched for studies reporting barriers or facilitators to individuals' engaging in formal psychological help-seeking for common mental health disorders in country members of ASEAN.
J Appl Res Intellect Disabil
September 2025
Department of Pedagogy, Faculty of Education and Social Work, University of Valladolid, Valladolid, Spain.
Background: Mental health (MH) problems are more common in people with intellectual disabilities (ID), yet under-diagnosis persists, which may be partly due to a lack of appropriate assessment tools. This study presents a systematic review of instruments used to assess MH problems in Spanish-speaking adults with ID.
Method: Following PRISMA guidelines, a search was conducted in Web of Science, PsycINFO, and Scopus using terms related to ID, MH and assessment.
Front Neurosci
August 2025
Beijing Life Science Academy, Beijing, China.
Hypocretin, also known as orexin, is a hypothalamic neuropeptide that regulates essential physiological processes including arousal, energy metabolism, feeding behavior, and emotional states. Through widespread projections and two G-protein-coupled receptors-HCRT-1R and HCRT-2R-the hypocretin system exerts diverse modulatory effects across the central nervous system. The role of hypocretin in maintaining wakefulness is well established, particularly in narcolepsy type 1 (NT1), where loss of hypocretin neurons leads to excessive daytime sleepiness and cataplexy.
View Article and Find Full Text PDFAJOG Glob Rep
August 2025
Department of Gynecology and Obstetrics, The Fourth Affiliated Hospital of Soochow University, Suzhou, China (Jin, Zhang and Hou).
Objectives: To assess the potential impact of years of education, which serves as a measure of socioeconomic inequality, on the occurrence of endometriosis, and to quantify the potential influence of modifiable factors as mediators.
Methods: The study used SNPs as genetic tools for genetic association. Analysis using 2-sample univariate and multivariate Mendelian randomization methods.