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Behavior change theory was used to explore predictors of long-term adherence (≥2 years) to exercise. A retrospective analysis of data from participants ( = 97) who reached a 6-month follow-up, which served as the baseline, was evaluated for completion of yearly follow-up surveys. Variables examined at baseline, which included age, race, gender, body mass index (BMI), and self-report of comorbidities, symptoms, physical function, and a Barriers Specific Self-Efficacy Scale, were examined with significance set at < .05. Lower BMI (29.1 ± 5.1 vs. 31.6 ± 6.5, = .047) and higher self-efficacy to overcome environmental barriers ( = .016) and social isolation ( = .05) were associated with long-term adherence. Self-efficacy to overcome environmental and social barriers, such as inclement weather, access to exercise site, and opportunities for group-based exercise, should be addressed to promote long-term adherence to exercise among older adults.
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http://dx.doi.org/10.1177/0733464819874954 | DOI Listing |
J Cancer Surviv
September 2025
Department of Medical BioSciences, Radboud University Medical Center, Nijmegen, 6525, GA, The Netherlands.
Purpose: Adolescents and young adults (AYAs) with cancer face unique long-term social and health challenges that impact their health-related quality of life (HRQoL). This study explores the association between lifestyle behaviors (physical activity, body composition, and nutrition) and HRQoL as well as fatigue in AYA cancer survivors.
Methods: The cross-sectional SURVAYA study analyzed data from long-term AYA cancer survivors (5-20 years post diagnosis, aged 18-39 at diagnosis) in The Netherlands.
J Invest Dermatol
September 2025
Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA; Sibel Health, Chicago, Illinois, USA; Querrey Simpson Institute for Bioelectronics, Northwestern University, Evanston, Illinois, USA. Electronic address:
The integration of wearable medical devices and digital health technologies (DHTs) in health care has grown significantly during the past 2 decades, particularly in dermatology, in which objective measurement of symptoms such as itch remains challenging. This review examines the evolution of DHTs in dermatology, focusing on the validation frameworks necessary for their implementation in clinical trials and research. We discuss the key stages of validation: hardware validation to ensure device reliability, analytical validation to transform raw sensor data into meaningful metrics, and clinical validation to demonstrate utility in specific patient populations.
View Article and Find Full Text PDFJ Alzheimers Dis Rep
September 2025
Epidemiology, IQVIA, Frankfurt am Main, Germany.
Background: Despite the availability of these therapies, maintaining long-term adherence remains a significant challenge.
Objective: This retrospective cohort study aimed to investigate 12-month and 5-year persistence with antidementia drug therapy in Germany and to examine the association between demographic and clinical variables and the risk of therapy discontinuation.
Methods: Patients aged 60 years or older from the IQVIA Longitudinal Prescription Database who received an initial prescription for antidementia therapy between 2016 and 2023 (index date) were included.
Cardiovasc Ther
September 2025
Department of Cardiology, Tianjin University Chest Hospital, Tianjin, China.
Hypertension constitutes a major risk factor for cardiovascular diseases. Globally, the management and control of hypertension remain suboptimal. At present, pharmacological intervention is a critical strategy for patients with hypertension to achieve blood pressure regulation.
View Article and Find Full Text PDFFront Bioeng Biotechnol
August 2025
The Third People's Hospital Affiliated to Fujian University of Traditional Chinese Medicine, Fuzhou City, Fujian, China.
Objective: This study investigates the biomechanical effects of long-term Tai Chi practice on the knee meniscus through biomechanical experimentation and finite element simulation, focusing on practitioners performing Knee Brushing and Twisting Step. The findings aim to establish scientific guidelines for optimizing exercise protocols in middle-aged and elderly populations.
Methods: Twenty male middle-aged and elderly practitioners were recruited, divided into a Beginner Group (BG: n = 10), and an Experienced Group (EG: n = 10).