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The development of smart biomedical implants with intrinsic communication system between sensors and actuators, or between implant and patient, remains a challenge for scientific community. Titanium and its alloys, especially Ti6Al4V, are the most used materials in the implant's fabrication. The present work is concerned with implant internal communication printing process and presents a detailed study on titanium alloy (Ti6Al4V) surface texturing and their characterization (morphological and chemical) produced by a Nd: YAG laser, aiming to create localized electrical insulation zones, necessary to accommodate electrical communication systems. The characterization of the textured surface was carried out by scanning electron microscopy and the heat affected zone was analyzed by X-ray diffraction. The results showed the formation of α-Ti, TiO and TiO phases on the textured surface. Through simulations in TINA software, the outer oxide layer formed during laser texturing had efficiency above 90% as insulator when an electrical current was applied.
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http://dx.doi.org/10.1016/j.msec.2019.109901 | DOI Listing |
J Thromb Thrombolysis
September 2025
Central Laboratory of Yongchuan Hospital, Chongqing Medical University, No. 439, Xuanhua Road, Yongchuan District, Chongqing, 402160, China.
In vitro assessment of the inhibitory effect of antiplatelet drugs on platelet aggregation is frequently employed to guide personalized antiplatelet therapy in clinical practice. However, existing methods for detecting platelet aggregation rely heavily on high concentrations of exogenous agonists, which may obscure part of the inhibitory effect of antiplatelet drugs and lead to an underestimation of their effects. This study validates a novel analytical strategy for evaluating the effects of antiplatelet drugs by quantifying the microscopic three-dimensional morphological parameters of platelet aggregates formed through spontaneous aggregation on a glass surface.
View Article and Find Full Text PDFRev Sci Instrum
September 2025
SLAC National Accelerator Laboratory, Menlo Park, California 94025, USA.
We report on the development of a robust microfluidic nozzle capable of generating replenishing liquid sheet targets with sub-micron thickness at up to kHz repetition rates, a λ/20 surface flatness over areas of at least 100 μm2, and in-vacuum dimensions of 6 × 1.5 mm2. The platform was evaluated for stability under hundreds of 4.
View Article and Find Full Text PDFJ Refract Surg
September 2025
Department of Refractive Surgery, Shanghai Aier Eye Hospital, Shanghai.
Purpose: To analyze the effects of ablation interruption on ablation depths and clinical refractive outcomes to characterize the impact of ambient temperature changes and ablation interruption on ocular surface temperature (OST) during excimer laser ablation.
Methods: This prospective study was conducted on laser ablations in polymethylmethacrylate (PMMA) plates and porcine corneas to simulate laser in situ keratomileusis (LASIK) treatments using the EX500 laser (Alcon Laboratories, Inc) at ambient temperatures of 18, 20, and 22 °C. Ablation interruption was performed for 1, 2, 3, 4, and 5 seconds at the 10th second of the treatment of -9.
Adv Sci (Weinh)
September 2025
School of Mechanical & Automotive Engineering, South China University of Technology, Guangzhou, 510641, China.
Recently, flexible airflow sensors have attracted significant attention due to their impressive characteristics and capabilities for airflow sensing. However, the development of high-performance flexible airflow sensors capable of sensing airflow over large areas remains a challenge. In this work, it is proposed that a hair-like flexible airflow sensor, based on laser direct writing and electrostatic flocking, offers an efficient technology for airflow sensing.
View Article and Find Full Text PDFArch Esp Urol
August 2025
Department of Urology and Guangdong Key Laboratory of Urology, First Affiliated Hospital of Guangzhou Medical University, 510230 Guangzhou, Guangdong, China.
Objectives: This study aims to assess the efficacy and safety of five categories of intracorporeal lithotripsy devices in percutaneous nephrolithotomy (PCNL): Pneumatic lithotripters, ultrasonic lithotripters, double-probe dual-energy lithotripters, single-probe dual-energy (SPDE) lithotripters and lasers.
Methods: A network meta-analysis was conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines. PubMed, Embase and Cochrane were utilised to search for randomised controlled trials (RCTs) up to 10 August 2024.