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Article Abstract
An efficient, catalyst-free strategy to construct diarylmethyl sulfones via 1,6-conjugate addition/aromatization/sulfonylation reaction of -quinone methides with sulfonyl hydrazides under mild and environmentally benign conditions has been developed. The established protocol provided a highly chemo- and regioselectivity synthesis of a diverse array of novel diarylmethyl sulfones with excellent yields, and the reaction could be scaled up.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6641250 | PMC |
| http://dx.doi.org/10.1021/acsomega.7b01745 | DOI Listing |
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Selective sulfonylation and isonitrilation of -quinone methides employing TosMIC as a source of sulfonyl group or isonitrile group.
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