Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Precision cancer medicine requires effective genotyping of every patient's tumor to optimally design treatment plans. Despite its imperfect sensitivity, the rapidity and convenience of cell-free DNA sequencing makes it an essential complement to tumor genotyping, which, when used appropriately, can aid the pursuit of effective genotyping for all patients..
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6679798 | PMC |
| http://dx.doi.org/10.1158/1078-0432.CCR-19-1233 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Resolving a century-old enigma: potato 'Bolters' originate from instability of the StCDF1.3 allele.
Theor Appl Genet
September 2025
Plant Breeding, Wageningen University & Research, P.O. Box 386, 6700 AJ, Wageningen, The Netherlands.
Potato bolters are caused by excision of a transposon from the StCDF1.3 allele, resulting in a somatic mutant with late maturity. Somatic mutations during vegetative propagation can lead to novel genotypes, known as sports.
View Article and Find Full Text PDFANASFV: a workflow for African swine fever virus whole-genome analysis.
Microb Genom
September 2025
Department of Infectious Diseases and Public Health, Jockey Club College of Veterinary Medicine and Life Sciences, City University of Hong Kong, Hong Kong, PR China.
African swine fever virus (ASFV) is highly transmissible and can cause up to 100% mortality in pigs. The virus has spread across most regions of Asia and Europe, resulting in the deaths of millions of pigs. A deep understanding of the genetic diversity and evolutionary dynamics of ASFV is necessary to effectively manage outbreaks.
View Article and Find Full Text PDFBackground: A significant surge in pertussis cases since early 2023 has raised serious public health concerns. To investigate the potential mechanisms contributing to this increased prevalence, we collected throat swab specimens from children exhibiting pertussis symptoms and conducted detailed molecular characterization.
Methods: All Bordetella pertussis (B.
Orthohantavirus rodent hosts and genotypes in Southern South America: A narrative review.
PLoS Negl Trop Dis
September 2025
Instituto de Diversidad y Ecología Animal (IDEA), CONICET and Universidad Nacional de Córdoba, Córdoba, Córdoba, Argentina.
Orthohantaviruses, family Hantaviridae, are zoonotic agents that pose a significant public health threat, particularly in South America, where they cause severe respiratory illnesses in humans. Despite their importance, knowledge gaps remain regarding the distributions of both the viruses and their rodent hosts in Southern South America, a region characterized by a great complexity of viral genotypes and reservoirs. This review provides an updated overview of orthohantavirus hosts and their associated viral genotypes in Argentina, Chile, Paraguay, and Uruguay.
View Article and Find Full Text PDFUnraveling the link: Is Parkinson's disease a causal factor for glaucoma? Insights from Mendelian randomization.
Sci Prog
September 2025
Xiamen Eye Center and Eye Institute of Xiamen University, School of Medicine, Xiamen, China.
BackgroundGlaucoma is recognized as the second-leading cause of complete blindness in developed countries and a significant contributor to irreversible vision loss worldwide. Understanding the potential genetic links between neurodegenerative diseases, such as Parkinson's disease, and glaucoma is crucial for developing preventive strategies.MethodsThis study utilized data from Genome-Wide Association Studies databases, focusing on European populations without gender restrictions.
View Article and Find Full Text PDF