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Article Abstract

A pair of new clerodane diterpenoid epimers, 3-methoxyl-teucvin () and 3-methoxyl-teucvin (), were isolated from the Roots of Their structures were completely established on the basis of spectroscopic methods, and the absolute configurations were determined by analysis of electronic circular dichroism (ECD) spectroscopy and X-ray diffraction analysis. Compounds and exhibited anti-inflammatory activities with IC values of 0.82 and 0.54 μM, respectively, while the IC value of dexamethasone as a positive control was found to be 0.14 μM.

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http://dx.doi.org/10.1080/14786419.2019.1601193DOI Listing

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