A pair of new -clerodane diterpenoid epimers from the roots of and their anti-inflammatory.

A pair of new clerodane diterpenoid epimers, 3-methoxyl-teucvin () and 3-methoxyl-teucvin (), were isolated from the Roots of Their structures were completely established on the basis of spectroscopic methods, and the absolute configurations were determined by analysis of electronic circular dichroism (ECD) spectroscopy and X-ray diffraction analysis. Compounds and exhibited anti-inflammatory activities with IC values of 0.82 and 0.

Ervatamines A-I, Anti-inflammatory Monoterpenoid Indole Alkaloids with Diverse Skeletons from Ervatamia hainanensis.

Nine new monoterpenoid indole alkaloids, ervatamines A-I (1-9), and five known ones (10-14), were isolated from Ervatamia hainanensis. The new structures were elucidated by extensive spectroscopic analysis and comparison to known compounds. Their absolute configurations were determined by various methods including computational methods, X-ray diffraction analysis, and electronic circular dichroism spectroscopy, as well as chemical transformations.