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is an important fungal pathogen that causes apple ring rot, which can significantly reduce apple yield. Fungicide applications are the main control measure of apple ring rot worldwide. Pyraclostrobin is a quinone outside inhibitor (QoI) fungicide that has yet to be registered for control of in China. Baseline sensitivity of to pyraclostrobin (EC of mycelial growth inhibition) was assessed for 97 isolates collected in Shandong Province. The EC values ranged from 0.7010 to 7.1378 μg/ml with the mean value of 3.0870 μg/ml and displayed a unimodal frequency distribution. After cultured on fungicide-free PDA medium or on apples for multiple generations, the -resistant isolates (RS) remained resistant to pyraclostrobin, but exhibited similar virulence as the susceptible isolates (S). Cross-resistance investigation revealed that pyraclostrobin was not cross-resistant to tebuconazole, flusilazole, carbendazim, and iprodione. Field evolution showed that pyraclostrobin at 200 and 250 g a.i./ha provided greater than 80% control efficacy against apple ring rot disease when applied as a therapeutic or preventive fungicide. The efficacy was similar to fungicides that have been registered for apple.
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http://dx.doi.org/10.1094/PDIS-07-18-1214-RE | DOI Listing |
Clin Exp Allergy
August 2025
Allergy-Vigilance Network, Nancy, France.
Background: The European Regulation list on mandatory labelling of foods includes 14 allergenic foods; however, other foods are also frequently implicated in food-induced anaphylaxis (FIA).
Methods: We analysed FIA cases reported to the Allergy Vigilance Network from 2002 to 2023. Allergenic foods involved in ≥ 1% of cases and not included in the list were assessed as emerging food allergens (EFA).
Adv Sci (Weinh)
August 2025
State Key Laboratory for Crop Stress Resistance and High-Efficiency Production, College of Plant Protection, Northwest A&F University, Yangling, Shaanxi, 712100, China.
Fungal small RNAs (sRNAs) represent a novel class of effector molecules in plant-pathogen interactions. However, understanding of how plants counteract fungal sRNAs-mediated trans-kingdom RNA interference (RNAi) in plant immunity remains limited. In previous study, a milRNA (Vm-milR1) from Valsa mali can be found to transboundary inhibit the expression of disease-resistance genes MdRLKT1 and MdRLKT2 in apple.
View Article and Find Full Text PDFHeart Rhythm O2
June 2025
Department of Cardiology, Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom.
Background: Wearable devices are widely used for atrial fibrillation (AF) detection, yet most validation studies include only sinus rhythm or AF, likely overestimating diagnostic performance.
Objective: This multicenter study assessed the performance of automated AF detection and physician interpretation of single-lead electrocardiograms (SL-ECGs) from the Apple Watch and CART Ring.
Methodology: Participants underwent simultaneous 12-lead ECG and SL-ECGs from Apple Watch and CART Ring.
Biosci Biotechnol Biochem
July 2025
Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo, JAPAN.
Labor shortages threaten global apple production, thereby encouraging new strategies to improve orchard management. The growth of columnar apples, controlled by the MdDOX-Co gene, enables vertical growth with minimal lateral branching, allowing for high-density planting and easier harvesting. MdDOX-Co encodes 2-oxoglutarate-dependent dioxygenase (2ODD, DOX).
View Article and Find Full Text PDFAquac Nutr
June 2025
Institute for Animal Ecology and Systematics, Justus Liebig University Giessen, Heinrich-Buff-Ring 26, Giessen 35392, Germany.
Shrimp aquaculture often has a large environmental footprint, partly due to the fish meal content of commercial shrimp feeds. One potential way to improve ecological sustainability would be to replace fish meal-based compounds in shrimp feeds with insect-based compounds, such as black soldier fly (BSF; s.l.
View Article and Find Full Text PDF