Publications by authors named "Alexander James Sharp"
Background: Wearable devices are widely used for atrial fibrillation (AF) detection, yet most validation studies include only sinus rhythm or AF, likely overestimating diagnostic performance.
Objective: This multicenter study assessed the performance of automated AF detection and physician interpretation of single-lead electrocardiograms (SL-ECGs) from the Apple Watch and CART Ring.
Methodology: Participants underwent simultaneous 12-lead ECG and SL-ECGs from Apple Watch and CART Ring.
Background: Atrial fibrillation (AF) is a major cause of stroke, with dynamic thromboembolic risk during and shortly after episodes. Implantable cardiac monitors and wearable devices have emerged as tools for real-time AF detection, yet their comparative performance in supporting anticoagulation strategies remains underexplored.
Objective: This single-center feasibility study investigated the performance of real-time AF detection and notification for episodes lasting longer than 30 minutes.
Aims: In patients with a low AF burden and long periods of sinus rhythm, 'pill-in-the-pocket' oral anticoagulation (OAC) may, taken as needed in response to AF episodes, offer the same thromboembolic protection as continuous, life-long OAC, while reducing bleeding complications at the same time. The purpose of this study is to systematically summarise available evidence pertaining to the feasibility, safety and efficacy of pill-in-the-pocket OAC.
Methods: Medline and Embase were searched from inception to July 2022 for studies adopting a pill-in-the-pocket OAC strategy in AF patients guided by daily rhythm monitoring (PROSPERO/CRD42020209564).