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This study investigates physical responses to force perturbations while tracking a moving target. The results show accuracy depends on the direction of a force perturbation and speed of the task, but generally not on hand. There are also differences in responses when the force is first applied and when it is removed.
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http://dx.doi.org/10.1109/TOH.2019.2912375 | DOI Listing |
Sports Biomech
September 2025
Motion Analysis and Integrative Neurophysiology Lab, College of Health and Human Services, The University of Toledo, Toledo, OH, USA.
Running over 'softer' surfaces is thought to lower the magnitude of impact forces. Current research is limited and inconclusive regarding the influence that transitioning between surfaces has on impact forces. Adult runners ( = 18) ran outdoors over a 50 m pathway that was half concrete and half grass at a self-selected speed.
View Article and Find Full Text PDFMol Biol Rep
September 2025
Chitkara College of Pharmacy, Chitkara University, Rajpura, 140401, Punjab, India.
Neuroinflammation, a vital protective response for tissue homeostasis, becomes a detrimental force when chronic and dysregulated, driving neurological disorders like Alzheimer's, Parkinson's, and Huntington's diseases. Potassium (K) channels maintain membrane potential and cellular excitability in neurons and glia within the intricate CNS signaling network. Neuronal injury or inflammation can disrupt K channel activity, leading to hyperexcitability and chronic pain.
View Article and Find Full Text PDFNucleic Acids Res
September 2025
Department of Biosciences & Bioengineering, IIT Bombay, Mumbai 400076, India.
Embryonic stem cells (ESCs), which are susceptible to DNA damage, depend on a robust and highly efficient DNA damage response (DDR) mechanism for their survival. However, the implications of physical force-mediated DNA damage on ESC fate remain unclear. We show that stiffness-dependent spreading of mouse ESCs (mESCs) induces DNA damage through nuclear compression, with DNA damage causing differentiation through Lamin A/C.
View Article and Find Full Text PDFAdv Mater
September 2025
Faculty of Chemistry, Adam Mickiewicz University, Uniwersytetu Poznańskiego 8, Poznań, 61-614, Poland.
AlN is a core material widely used as a substrate and heat sink in various electronic and optoelectronic devices. Introducing luminescent properties into intrinsic AIN opens new opportunities for next-generation intelligent sensors, self-powered displays, and wearable electronics. In this study, the first evidence is presented of AlN crystals exhibiting satisfactory mechanoluminescence (ML), photoluminescence (PL), and afterglow performance, demonstrating their potential as novel multifunctional optical sensors.
View Article and Find Full Text PDFAdv Mater
September 2025
Department of Engineering Science, University of Oxford, Oxford, OX1 3PJ, UK.
Hydrogen embrittlement (HE) poses a significant challenge to the durability of materials used in hydrogen production and utilization. Disentangling the competing nanoscale mechanisms driving HE often relies on simulations and electron-transparent sample techniques, limiting experimental insights into hydrogen-induced dislocation behavior in bulk materials. This study employs in situ Bragg coherent X-ray diffraction imaging to track three-dimensional (3D) dislocation and strain field evolution during hydrogen charging in a bulk grain of austenitic 316 stainless steel.
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