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Objectives: Our goals were to compare the outcome of the intra-atrial lateral tunnel (ILT) and the extracardiac conduit (ECC) techniques for staged total cavopulmonary connection (TCPC) and to compare the current modifications of the TCPC technique, i.e. the prosthetic ILT technique with the current ECC technique with a ≥18-mm conduit.
Methods: We included patients who had undergone a staged TCPC between 1988 and 2008. Records were reviewed for patient demographics, operative details and events during follow-up (death, surgical and catheter-based reinterventions and arrhythmias).
Results: Of the 208 patients included, 103 had the ILT (51 baffle, 52 prosthetic) technique and 105 had the ECC technique. Median follow-up duration was 13.2 years (interquartile range 9.5-16.3). At 15 years after the TCPC, the overall survival rate was comparable (81% ILT vs 89% ECC; P = 0.12). Freedom from late surgical and catheter-based reintervention was higher for patients who had ILT than for those who had ECC (63% vs 44%; P = 0.016). However, freedom from late arrhythmia was lower for patients who had ILT than for those who had ECC (71% vs 85%, P = 0.034). In a subgroup of patients who had the current TCPC technique, when we compared the use of a prosthetic ILT with ≥18-mm ECC, we found no differences in freedom from late arrhythmias (82% vs 86%, P = 0.64) or in freedom from late reinterventions (70% vs 52%, P = 0.14).
Conclusions: A comparison between the updated prosthetic ILT and current ≥18-mm ECC techniques revealed no differences in late arrhythmia-free survival or late reintervention-free survival. Overall, outcomes after the staged TCPC were relatively good and reinterventions occurred more frequently in the ECC group, whereas late arrhythmias were more common in the ILT group.
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http://dx.doi.org/10.1093/icvts/ivz081 | DOI Listing |
J Clin Med
August 2025
Gray Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv 6997801, Israel.
: We compared short- and long-term outcomes of patients with native left-sided infective endocarditis (IE) confined to the valve leaflet ("simple") versus those with perivalvular extension ("complex") over two decades. : From 2005 to 2024, 177 patients (mean age 59.6 ± 13.
View Article and Find Full Text PDFSeizure
August 2025
Department of Pediatrics, Division of Biochemical Genetics, BC Children's Hospital, Faculty of Medicine, University of British Columbia Vancouver, BC, Canada.
Adv Mind Body Med
August 2025
Professor, Symbiosis College of Nursing, Symbiosis International (Deemed University), Pune, India.
Background: Low back pain (LBP) is a prevalent issue affecting a significant portion of the global population, impacting the quality of life, especially in menopausal females.
Aim: This study aimed to assess the effectiveness of the Acharya Technique in managing LBP among late middle-aged females.
Methodology: The study used a pre-experimental research design.
Cureus
July 2025
Cardiovascular Surgery, Kawasaki Municipal Hospital, Kawasaki, JPN.
Objectives: Previous studies have demonstrated the advantages of mitral valve repair (MVP) in infective endocarditis (IE) in early and late outcomes. However, the influence of complexity in mitral valve surgery on long-term outcome is unclear. The purpose of this study was to clarify whether the severity of IE affects long-term outcome.
View Article and Find Full Text PDFRadiother Oncol
August 2025
Department of Radiation Oncology, Sunnybrook Odette Cancer Centre, Toronto, Ontario, Canada; Department of Radiation Oncology, University of Toronto, Toronto, Ontario, Canada. Electronic address:
Background And Purpose: Focal salvage high dose-rate (HDR) prostate brachytherapy has emerged as a standard option for radiorecurrent prostate cancer. However, long-term prospective data remains limited. Our prospective study aimed to explore the toxicities, health-related quality of life (HRQOL) and efficacy of focal salvage HDR prostate brachytherapy.
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