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Objective: To quantify the magnitude of the association between the type of vehicle and the probability of being responsible for a collision between two or more vehicles.
Method: From the registry of road crashes with victims maintained by the Spanish Traffic General Directorate (2014 and 2015), a matched case-control study was designed. Cases were offending drivers involved in the 27,630 collisions between two or more vehicles in which only one of the drivers had committed a driving mistake or offence. Each case was matched with the non-offending drivers of the vehicles involved in the same crash: in all, 31,219 controls were included. Apart from the commission of offences and the type of vehicle involved, we got information about other characteristics of the driver (age, sex, etc.) and about the vehicle (age). Odds ratios (OR) were calculated in order to quantify the association between each type of vehicle and the odds of being responsible for the collision, crude and adjusted (by conditioned logistic regression) by the rest of collected variables.
Results: In comparison with private cars, bicycles had a lower risk of causing a collision (adjusted OR: .30), and also mopeds (aOR: .52) and buses (aOR: .63). Vans (aOR: 1.19) and four-wheel vehicles (aOR: 1.33) increased the risk.
Conclusion: Two-wheeled vehicles and buses had a lower risk of causing collisions than private cars. This association is independent of some of the characteristics of the driver, as well as the age of the vehicle.
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http://dx.doi.org/10.1016/j.gaceta.2018.10.007 | DOI Listing |
Accid Anal Prev
September 2025
Industrial and Manufacturing Systems Engineering Department, University of Michigan-Dearborn, 4901 Evergreen Rd, Dearborn, 48128, MI, USA; University of Michigan Transportation Research Institute, 2901 Baxter Rd, Ann Arbor, 48109, MI, USA. Electronic address:
Pedestrian injuries remain a public health concern, with child pedestrians being particularly vulnerable due to their unique physical and cognitive characteristics. This study presents a comprehensive analysis comparing injury severity patterns between child (≤14 years) and non-child (>14 years) pedestrians using Lasso logistic regression and advanced machine learning techniques, specifically Catboost with SHAP (SHapley Additive exPlanations) values to interpret the models. By analyzing six years of national crash data from the Crash Report Sampling System (CRSS) from 2016 to 2021, we identify significant factors influencing injury outcomes for both age groups.
View Article and Find Full Text PDFPublic Health Rep
September 2025
VHA Homeless Programs Office, US Department of Veterans Affairs, Washington, DC, USA.
Objectives: Mobile medical units (MMUs) provide health care services in the community to reach populations with geographic, financial, and other barriers to care. The US Department of Veterans Affairs (VA) Homeless Patient Aligned Care Team (HPACT) program deployed MMUs to 25 sites in fiscal year 2024 to increase access for veterans experiencing homelessness. We examined early implementation of MMUs in HPACT sites by describing implementation and operational issues, services provided, and characteristics of veterans who used MMUs.
View Article and Find Full Text PDFPLoS One
September 2025
Department of Biology, Providence College, Providence, Rhode Island, United States of America.
In Npc1 deficient mice, postnatal developmental alterations in cerebellar microglia and Purkinje cells (PCs) are followed by early-onset neurodegeneration. Even in the absence of PC loss, microglia in Npc1nmf164 mice display hallmark features of activation during early postnatal development, including increased proliferation, enhanced phagocytic activity, and morphological changes indicative of an activated state. In this study, we investigated whether mammalian target of rapamycin complex 1 (mTORC1) drives postnatal activation of cerebellar microglia in Npc1nmf164 mice.
View Article and Find Full Text PDFRegular non-steroidal anti-inflammatory drug (NSAID) use increases stress fracture risk, but the mechanisms remain unclear. Here, we used Ptgs2-Y385F mice, which lack cyclooxygenase 2 (COX2) enzyme activity, to test the hypothesis that naproxen decreases strain adaptive bone remodeling in a COX2-dependent manner and decreases bone toughness and fracture resistance through COX2-independent effects. MicroCT and mechanical testing showed minimal baseline differences between Ptgs2-Y385F and wild-type (WT) mice.
View Article and Find Full Text PDFGenetic studies have linked (encoding soluble epoxide hydrolase, sEH) and (encoding cyclooxygenase-2, COX-2) to Alzheimer's disease (AD). Elevated levels of sEH and COX-2 found in AD patients and animals suggest their involvement in neurodegeneration, glial activation, vascular dysfunction, and inflammation. This study evaluated the effects of a new dual sEH/COX-2 inhibitor, PTUPB, on cerebrovascular function and cognition in TgF344-AD rats.
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