Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Epimeric catechin and epicatechin peracetates offer the possibility to explore the number of conformers needed for the absolute configuration determination without affecting the reliability of the assignment. Comparisons between experimental and DFT B3PW91/DGDZVP calculated curves showed that, in molecules.where the conformational flexibility generates a large number of conformers, it is possible to significantly reduce the number of conformers needed to generate VCD results that provide secure absolute configuration assignment.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Sesquiterpenoids from Euphorbia esula L.
Phytochemistry
September 2025
State Key Laboratory Basis of Xinjiang Indigenous Medicinal Plants Resource Utilization, Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Urumqi, 830011, People's Republic of China; University of Chinese Academy of Sciences, Beijing, 100049, People's Republic of Ch
Six undescribed sesquiterpene esters, euphoresulins A-F, along with fourteen known daucane analogues were isolated from the aerial parts of Euphorbia esula growing in Uzbekistan. Their structures were determined on the basis of extensive spectroscopic analyses, with absolute configurations established by comparison of experimental and calculated ECD data, in addition to single-crystal X-ray diffraction crystallography. Euphoresulins A-F (1-6) presented sesquiterpene ester types of daucane for euphoresulins A-D (1-4) and aromadendrane for euphoresulins E-F (5-6).
View Article and Find Full Text PDFTargeted discovery of sesquiterpene indole alkaloids from Greenwayodendron suaveolens.
Phytochemistry
September 2025
Équipe "Chimie des substances naturelles" BioCIS, CNRS, Université Paris-Saclay, 17, avenue des Sciences, 91400, Orsay, France. Electronic address:
Throughout the past decades, annonaceous plants have been of particular interest to the natural product community because of their therapeutic value and their richness in isoquinoline alkaloids. Taking advantage from our laboratory historical collection of these compounds, a MS/MS database of 322 isoquinolines and other metabolites from Annonaceae was implemented and named IQAMDB . The present report describes the dereplication of known alkaloids from stem barks of Greenwayodendron suaveolens (Engl.
View Article and Find Full Text PDFThe Semisynthesis of 27-Deoxywithaferin A and 4--5,6-Deoxywithaferin A from Withaferin A as Potential Antitumor Agents.
J Nat Prod
September 2025
Pharmaceutical College, Guangxi Medical University, Nanning, Guangxi 530021, PR China.
We describe two concise, three-step routes for the individual synthesis of 27-deoxywithaferin A () and 4--5,6-deoxywithaferin A () from withaferin A (). The protection strategy for the double bond of enone with thiophenol and the conjugate reduction of the epoxy group are important in generating these products, with an overall yield of 40%. The absolute configuration of 4--5,6-deoxywithaferin A () has been confirmed by X-ray crystallography.
View Article and Find Full Text PDFBioorganic chemistry of natural products that control plant pathogens.
J Pestic Sci
August 2025
Department of Chemistry for Life Sciences and Agriculture, Faculty of Life Sciences, Tokyo University of Agriculture.
Developing new agrochemicals is essential for sustainable agriculture and global food security. Our group focused on natural products that control plant pathogens, conducting synthetic research across three key areas of interest: antimicrobial compounds, phytoalexins, and microbial signaling molecules. We established new methods for producing chiral allylic alcohols as useful synthetic intermediates for natural product synthesis the enantioselective synthesis of antimicrobial agents such as peniciaculins.
View Article and Find Full Text PDFA new deep learning model for predicting IMRT dose distributions for lung cancer with dose masks.
Front Oncol
August 2025
Department of Radiation Oncology, Cancer Center, Peking University Third Hospital, Beijing, China.
Purpose: 3D U-Net deep neural networks are widely used for predicting radiotherapy dose distributions. However, dose prediction for lung cancer IMRT is limited to conventional radiotherapy, with significant errors in predicting the intermediate and low-dose regions.
Methods: We included a mixed dataset of conventional radiotherapy and simultaneous integrated boost (SIB) radiotherapy with various prescription schemes.