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Article Abstract

Study Design: Mixed retrospective and prospective cohort study.

Objectives: To determine 5-year survival after hospitalisation with spinal cord injury (SCI) in Bangladesh and to develop a prediction model to identify people at high risk of dying within 5 years.

Setting: Bangladesh.

Methods: Medical records were used to identify people with SCI admitted to a hospital in Bangladesh in 2011. Participants or their family members were contacted >5 years after discharge to determine vital status or date of death. Survival from time of discharge was estimated with Kaplan-Meier curves. A linear model of the log odds of death within 5 years of discharge was constructed and internally validated.

Results: Of the 345 people who were admitted and survived to discharge in 2011, 342 (99%) were accounted for 5 years later: 74 (22%) had died (survival = 78%; 95% CI 74-82%). Sixty nine of the 223 participants who were wheelchair-dependent at discharge had died (survival = 69%; 95% CI 62-75%). A parsimonious model predicted survival as a function of age and mode of mobility at discharge (wheelchair-dependent or ambulant). The odds of dying increased by a factor of 1.6 (95% CI, 1.3-2.0) with every decade of age and by a factor of 12.6 (95% CI, 4.8-32.9) if wheelchair-dependent. The model had good calibration and discrimination.

Conclusion: The risk of dying after discharge from hospital with SCI in Bangladesh is high, especially among older, wheelchair-dependent people. A simple prediction model discriminates those at high risk of dying within 5 years.

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http://dx.doi.org/10.1038/s41393-018-0211-yDOI Listing

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