Publications by authors named "Mohammad Sohrab Hossain"

Purpose: To assesses the reliability and validity of the Bengali version of the World Health Organization Disability Assessment Schedule 2.0 (WHODAS 2.0, 36-item) for individuals with spinal cord injury (SCI).

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Question: Is electrical stimulation (ES) combined with strength training and usual care more effective than usual care alone in increasing the strength of very weak muscles in people with recent spinal cord injury (SCI)?

Design: A randomised controlled trial with concealed allocation, intention-to-treat analysis and blinded outcome assessors.

Participants: Sixty participants with recent SCI were recruited from three SCI units in Australia and Bangladesh.

Interventions: Participants were randomised to either a treatment or control group.

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The study aims to explore the demographic and clinical characteristics of persons with spinal cord injury (SCI) in Bangladesh. A total of 3035 persons with SCI spanning from 2018 to 2022 were included in this cross-sectional study. Information about demographic and clinical variables was obtained from the medical records and verified through telephone calls to ensure accuracy and consistency.

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Article Synopsis
  • - The study investigates the health-related quality of life (QoL) and coping strategies among 2,198 COVID-19 survivors in Bangladesh, using door-to-door interviews and standardized questionnaires.
  • - Results show that males were more affected by COVID-19 than females, with various factors like age, marital status, occupation, and co-morbidities significantly influencing QoL across physical, psychological, and social dimensions.
  • - The main coping strategy identified among survivors was avoidant coping, followed by problem-focused coping, with emotional-focused coping being the least common; these strategies were also influenced by factors such as education and living area.
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Aim: The aim of this research is to focus on gaining an insight into the knowledge, attitudes, behavioural practises (KAP), and psychological impact relating to COVID-19 among the people living with spinal cord injury receiving in-patient rehabilitation.

Methods: A prospective, cross-sectional survey of people with SCI ( = 207), who were in active in-patient rehabilitation from two tertiary SCI Rehabilitation Centres in Bangladesh. Data were collected via face-to-face interviews, after voluntary consent, using a pretested, language validated questionnaire on Knowledge, Attitude and Behavioural practises (KAP) and the Depression, Anxiety, Stress Scale (DASS-21).

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Design: Cohort study embedded in a clinical trial.

Setting: Community, Bangladesh.

Objectives: To determine the incidence, severity and time course of pressure injuries over the first two years following discharge from hospital in people with spinal cord injuries (SCI) in Bangladesh.

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Background: The objective of this study was to identify the prevalence of long COVID symptoms in a large cohort of people living with and affected by long COVID and identify any potential associated risk factors.

Methods: A prospective survey was undertaken of an inception cohort of confirmed people living with and affected by long COVID (aged 18-87 years). 14392 participants were recruited from 24 testing facilities across Bangladesh between June and November 2020.

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Design: Descriptive.

Setting: Community, Bangladesh.

Objectives: To determine the costs associated with providing a community-based model of care delivered as part of the CIVIC trial to people discharged from hospital with recent spinal cord injury (SCI), and to determine the economic burden to households.

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Article Synopsis
  • A randomized controlled trial was conducted to assess the effectiveness of a community-based intervention aimed at preventing serious complications and death among individuals with spinal cord injuries in Bangladesh, 2 years post-discharge.
  • The study involved 410 participants, who were either placed in an Intervention group (receiving phone calls and home visits) or a Control group (receiving standard care), with no noticeable difference in survival rates or complications noted between the two groups after 2 years.
  • The conclusion highlighted that the community-based care approach, which included regular health professional contact, did not prove to be more effective than usual post-discharge care in reducing mortality or managing complications.
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Design: Mixed methods study SETTING: Community, Bangladesh OBJECTIVES: To understand how a community-based intervention for people with spinal cord injury (SCI) in Bangladesh was delivered as part of a randomised controlled trial and to gauge the perceptions of participants and healthcare professionals to the intervention.

Methods: A community-based intervention was administered to 204 participants as part of a large randomised controlled trial (called the CIVIC trial). Case-managers followed-up participants with regular telephone calls and home visits over the first 2 years after discharge.

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Study Design: Cross-sectional study.

Objectives: To determine the degree of impoverishment of people with spinal cord injury (SCI) and their families in Bangladesh caused by loss of work-related income following injury.

Setting: Spinal cord injury centre, Bangladesh.

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We aimed to describe the causes, types, and consequences of lower limb amputation and the demographics of subjects with such amputation who attended a tertiary rehabilitation center in Bangladesh, Centre for the Rehabilitation of the Paralysed. Cross-sectional data were collected from subjects with lower limb amputation who attended a specialized rehabilitation center between January 2014 and August 2016. Telephone interviews were conducted using a structured questionnaire.

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Study Design: Cross-sectional analysis of a mixed retrospective and prospective inception cohort study.

Objectives: To determine health status, quality of life and socioeconomic situation of people with spinal cord injuries (SCI) 6 years after discharge from a hospital in Bangladesh.

Setting: Bangladesh.

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Study Design: Mixed retrospective and prospective cohort study.

Objectives: To determine 5-year survival after hospitalisation with spinal cord injury (SCI) in Bangladesh and to develop a prediction model to identify people at high risk of dying within 5 years.

Setting: Bangladesh.

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Introduction: People with spinal cord injuries in low-income and middle-income countries are highly vulnerable to life-threatening complications in the period immediately after discharge from hospital. We are conducting a randomised controlled trial in Bangladesh to determine whether all-cause mortality at 2 years can be reduced if health professionals regularly ring and visit participants in their homes following discharge. We will conduct a process evaluation alongside the trial to explain the trial results and determine the feasibility of scaling this intervention up in low-income and middle-income countries if it is found to be effective.

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Study Design: Cross-sectional study.

Objectives: To identify socio-demographic and injury-related factors that contribute to activity limitations and participation restrictions in people with spinal cord injury (SCI) in Bangladesh.

Setting: Centre for the Rehabilitation of the Paralysed (CRP), Savar, Dhaka, Bangladesh.

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We have previously shown that amotosalen HCl (S-59 psoralen)-treated donor splenocytes, which have limited proliferative capacity in vitro, can protect major histocompatibility complex-mismatched bone marrow transplant (BMT) recipients from lethal murine cytomegalovirus infection without causing graft-versus-host disease. In this study, we further investigated the effects of amotosalen-treated donor T cells on immune reconstitution after allogeneic BMT. We were surprised to find that amotosalen-treated donor T cells persisted long-term in vivo, comprising 6% to 10% on average of the T-cell compartment of transplant recipients at 4 months after transplantation.

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