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We report a rare case of meningitis due to a combination of and . An 80-year-old female had a 4-year history of type II diabetes mellitus (DM) and an 11-year history of rheumatoid arthritis, which was treated with prednisolone, tacrolimus, and methotrexate. One month after the removal of a dental implant, she complained of a disturbance of consciousness and suffered a convulsion. A cerebrospinal fluid culture was found to be positive for both and . After 14 days of antibiotic treatment with 4 g/day ceftriaxone, her stiff neck, somnolence, and laboratory data greatly improved, and she was successfully discharged at 27 days after admission. Although both and are generally considered to be benign bacteria, they can cause meningitis in patients with the following risk factors: older age, on immunosuppressive treatment, DM, or dental treatment.
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http://dx.doi.org/10.1159/000490695 | DOI Listing |
Interv Neuroradiol
September 2025
Department of Neuroradiology, Rockefeller Neuroscience Institute, West Virginia University, Morgantown, WV, USA.
BackgroundChronic subdural hematoma (cSDH) is a common condition in older adults, often treated with surgical-evacuation, though recurrence rates can reach 30%. Middle meningeal artery embolization (MMAE) has emerged as a treatment alternative. Statins have been explored as adjunct therapies, but literature regarding their combined use with MMAE is limited.
View Article and Find Full Text PDFMath Biosci Eng
July 2025
Department of Mathematics and Applied Mathematics, University of the Western Cape, Private Bag X17, Bellville 7535, South Africa.
In this paper, we present a deterministic model for the population dynamics of HIV/AIDS, wherein some individuals at the severe symptomatic phase of HIV develop serious opportunistic infections (OIs) such cryptococcal, tuberculous, pneumococcal, and other bacterial meningitis due to an inappropriate treatment or lack of counseling. OIs are responsible for significant mortality and disability on individuals with HIV in many countries. Cryptococcal meningitis (CM) is among frequent OIs responsible for significant mortality and disability of individuals with HIV in limited resource settings.
View Article and Find Full Text PDFBrain Behav
September 2025
Department of Neurosurgery, The Third People's Hospital of Datong, Datong, China.
Background: Meningiomas, the second most common intracranial tumors, account for over one-third of primary central nervous system tumors. Recent studies suggest a link between trace elements, nutrients, and tumor development. This study used Mendelian randomization (MR) to investigate causal links between trace elements, nutrients, and meningioma.
View Article and Find Full Text PDFMedicine (Baltimore)
August 2025
Department of Orthopedics, Xiangtan Central Hospital, Xiangtan, Hunan Province, China.
Rationale: Cryptococcal meningitis is caused by Cryptococcus neoformans and Cryptococcus gattii, predominantly affects immunocompromised host. Resistance to amphotericin B poses therapeutic challenges, especially in immunocompetent individuals, where evidence is scarce.
Patient Concerns: This study reports a case of an old immunocompetent male diagnosed with amphotericin B-resistant C neoformans meningitis.
PLoS One
August 2025
Disease Dynamics Unit, University of Cambridge, Cambridge, United Kingdom.
The introduction of MenAfriVac has significantly reduced group A meningococcal meningitis in the African meningitis belt, but epidemics caused by other groups such as C, W, Y and X (MenCWYX) remain a threat. To address this, a new multivalent meningococcal conjugate vaccine (MMCV) has been developed and pre-qualified by WHO. This study extends a previously established transmission dynamic model for MenA to include MenCWYX, enabling evaluation of the potential impact of MMCVs under various vaccination strategies.
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