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The Juvenile Arthritis Multidimensional Assessment Report (JAMAR) is a new parent/patient reported outcome measure that enables a thorough assessment of the disease status in children with juvenile idiopathic arthritis (JIA). We report the results of the cross-cultural adaptation and validation of the parent and patient versions of the JAMAR in the Turkish language. The reading comprehension of the questionnaire was tested in 10 JIA parents and patients. Each participating centre was asked to collect demographic, clinical data and the JAMAR in 100 consecutive JIA patients or all consecutive patients seen in a 6-month period and to administer the JAMAR to 100 healthy children and their parents. The statistical validation phase explored descriptive statistics and the psychometric issues of the JAMAR: the 3 Likert assumptions, floor/ceiling effects, internal consistency, Cronbach's alpha, interscale correlations, test-retest reliability, and construct validity (convergent and discriminant validity). A total of 466 JIA patients (13.7% systemic, 40.6% oligoarticular, 22.5% RF negative poly-arthritis, and 23.2% other categories) and 93 healthy children were enrolled in four centres. The JAMAR components discriminated well-healthy subjects from JIA patients. All JAMAR components revealed good psychometric performances. In conclusion, the Turkish version of the JAMAR is a valid tool for the assessment of children with JIA and is suitable for use both in routine clinical practice and clinical research.
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http://dx.doi.org/10.1007/s00296-018-3982-8 | DOI Listing |
Lancet Reg Health West Pac
September 2025
Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, China.
Background: There is ongoing controversy as to whether surgical intervention to haematoma evacuation benefits patients with acute intracerebral haemorrhage (ICH). This study aimed to evaluate the association of surgical intervention to evacuate the haematoma and 6-month functional outcome in participants of the third Intensive Care Bundle with Blood Pressure Reduction in Acute Cerebral Haemorrhage Trial (INTERACT3).
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Front Pediatr
August 2025
Department of Pediatrics, Affiliated Hospital of Inner Mongolia Medical University, Hohhot, Inner Mongolia, China.
Background And Objective: This study aims to analyze the clinical characteristics of anti-GABAR encephalitis in pediatric patients. Due to its rarity and diagnostic challenges in children, we compare clinical features between adult and pediatric cases.
Materials And Methods: Using the key words "anti-GABAR encephalitis, children, autoimmune encephalitis, limbic encephalitis", we conduct a comprehensive literature review of all studies related to anti-GABAR encephalitis published from January 2010 to January 2024.
Adv Healthc Mater
September 2025
National Engineering Laboratory for Modern Silk, College of Textile and Clothing Engineering, Soochow University, Suzhou, 215123, China.
Melasma is a facial hyperpigmentation disease that significantly impacts patients' quality of life. Clinical treatment is limited by the short half-lives and hydrophilicity of drugs, necessitating release curve optimization to maintain a stable therapeutic concentration for an extended period. This article utilizes natural biomaterials to design a core-shell structured microneedle, combining the "immediate release" and "delayed release" module to achieve programmed drug release.
View Article and Find Full Text PDFJ Affect Disord
September 2025
NHC Key Laboratory of Environment and Endemic Diseases, School of Public Health, Health Science Center, Xi'an Jiaotong University, Xi'an, Shaanxi, 710061, China; Collaborative Innovation Center of Endemic Diseases and Health Promotion in Silk Road Region, Xi'an, Shaanxi, 710061, China. Electronic ad
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J Psychiatr Res
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Laboratory of Biological Psychiatry, Institute of Mental Health, Tianjin Anding Hospital, Mental Health Center of Tianjin Medical University, Tianjin, 300222, China. Electronic address:
Background: The duration of untreated psychosis (DUP) is a critical factor influencing long-term outcome in schizophrenia (SCZ). Its short-term effects during early treatment remain less well characterized.
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