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Introduction: Neck pain and torticollis are common symptoms in the pediatric population that rarely requires further investigation. However, in case symptoms persist, then a more meticulously approach should be considered. Underlying conditions such as infections, neck injury, autoimmune disorders or even cervical spine cancer should be excluded from diagnosis. Cervical spine cancer is a rare neurosurgical entity in the pediatric population and even rarer is atlantoaxial Ewing's sarcoma. In this report, we present a rare case of primary Ewing's sarcoma of the axis.
Case Report: A 3.5-year-old female with progressive neck pain and intermittent episodes of torticollis was referred to our outpatient clinic. Imaging studies revealed a malignant tumor located on C2 vertebra. Diagnosis of Ewing's Sarcoma was confirmed via open biopsy and the patient was treated with Euro-EWING 99 chemotherapy.
Conclusion: Pediatric neck pain and/or torticollis should raise high suspicion for malignancy of cervical spine. Modern diagnostic means and techniques can assist in the screening and diagnosis of these tumors.
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http://dx.doi.org/10.1016/j.pjnns.2018.02.005 | DOI Listing |
Nature
September 2025
Department of Translational Genomics, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.
Small cell lung cancer (SCLC) is a highly aggressive type of lung cancer, characterized by rapid proliferation, early metastatic spread, frequent early relapse and a high mortality rate. Recent evidence has suggested that innervation has an important role in the development and progression of several types of cancer. Cancer-to-neuron synapses have been reported in gliomas, but whether peripheral tumours can form such structures is unknown.
View Article and Find Full Text PDFInt J Surg Case Rep
August 2025
CHU Joseph Ravoahangy Andrianavalona, Service de Chirurgie Orthopédique et Traumatologique, 101 Tananarive, Madagascar.
Introduction And Importance: Monteggia lesions combine a fracture of the ulna with dislocation of the radial head. Monteggia-like variants add a radial head fracture. We report a unique Monteggia-like injury with a bifocal radial fracture and subcutaneous enucleation of the radial neck, which does not fit existing classifications.
View Article and Find Full Text PDFJ Am Coll Health
September 2025
Department of Family Medicine (Student Health), Duke University, Durham, North Carolina, USA.
The authors describe a case of vertebral artery dissection in a patient with Turner Syndrome presenting to a university student health center. Cervical artery dissection (CeAD) is the most common cause of stroke in young adults and should be considered in patients with underlying risk factors. It usually presents with local symptoms caused by compression of adjacent nerves and their feeding vessels, as well as ischemia and hemorrhagic events.
View Article and Find Full Text PDFBraz Oral Res
September 2025
Universidade de Ribeirão Preto - Unaerp, Graduate Program in Dentistry, Ribeirão Preto, SP, Brazil.
The aim of this study was to assess the prevalence of temporomandibular disorder (TMD) and associated factors in an adult population in southern Brazil. The population-based sample (n = 4.65) included participants from Passo Fundo, a town in southern Brazil.
View Article and Find Full Text PDFDisabil Rehabil
September 2025
Faculty of Business and Social Sciences, University of Applied Sciences, Osnabrück, Germany.
Purpose: To summarize the evidence on the effectiveness of manual therapy (MT) and exercise targeted to the neck or jaw and neck (combined) in the management of orofacial pain (OFP).
Material And Methods: The protocol was registered in PROSPERO (CRD42021227490). Electronic searches were conducted in MEDLINE, EMBASE, Cochrane Library, Web of Science, SCOPUS, and CINAHL.