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This paper extends on previous research on the extraction and statistical analysis on relevant dynamic features (width, grayscale and radian combined with writing sequence information) in forensic handwriting examinations. In this paper, a larger signature database was gathered, including genuine signatures, freehand imitation signatures, random forgeries and tracing imitation signatures, which are often encountered in casework. After applying Principle Component Analysis (PCA) of the variables describing the proximity between specimens, a two-dimensional kernel density estimation was used to describe the variability of within-genuine comparisons and genuine-forgery comparisons. We show that the overlap between the within-genuine comparisons and the genuine-forgery comparisons depends on the imitated writer and on the forger as well. Then, in order to simulate casework conditions, cases were simulated by random sampling based on the collected signature dataset. Three-dimensional normal density estimation was used to estimate the numerator and denominator probability distribution used to compute a likelihood ratio (LR). The comparisons between the performance of the systems in SigComp2011 (based on static features) and the method presented in this paper (based on relevant dynamic features) showed that relevant dynamic features are better than static features in terms of accuracy, false acceptance rate, false rejection rate and calibration of likelihood ratios.
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http://dx.doi.org/10.1016/j.forsciint.2017.11.022 | DOI Listing |
Appl Biosaf
August 2025
Global Center for Health Security, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Introduction: Laboratory-acquired infections (LAIs) from exposure to infectious biological pathogens during laboratory operations present ongoing challenges despite modern biosafety measures. Notably, LAIs attributed to inhaling infectious aerosols continue to occur.
Objective: This review aims to enhance understanding of the risks of LAIs associated with infectious aerosols.
Wellcome Open Res
August 2025
Paul G. Allen School for Global Health, Washington State University, Pullman, Washington, USA.
Arenaviruses and Hantaviruses, primarily hosted by rodents and shrews, represent significant public health threats due to their potential for zoonotic spillover into human populations. Despite their global distribution, the full impact of these viruses on human health remains poorly understood, particularly in regions like Africa, where data is sparse. Both virus families continue to emerge, with pathogen evolution and spillover driven by anthropogenic factors such as land use change, climate change, and biodiversity loss.
View Article and Find Full Text PDFHealth Policy Plan
September 2025
Regional Emergency Director, WHO Health Emergencies Department, WHO South-East Asian Regional Office, New Delhi, India.
Zoonotic influenzas are major, ongoing public health policy challenge, not the least because of the importance of functional multisector partnerships (MSPs) for their prevention and control. However, despite years of investment in developing them, many countries have found multisectoral approaches, such as One Health, difficult to operationalise at national and sub national levels. One explanation for the lack of uptake is the limited nature of guidance on the design and adaptation of MSPs that consider local institutional dynamics.
View Article and Find Full Text PDFDev Growth Differ
September 2025
Laboratory for Epithelial Morphogenesis, RIKEN Center for Biosystems Dynamics Research, Kobe, Japan.
Multicellular organisms generate organizational complexity through morphogenesis, in which mechanical forces orchestrate the movements and deformations of cells and tissues, while chemical signals regulate the molecular events that generate and coordinate these forces. One common denominator that is critical both for mechanics and biochemistry is material property. Material properties define how materials deform or rearrange under applied forces, and how rapidly molecules interact or spread in space and time.
View Article and Find Full Text PDFJ Am Chem Soc
September 2025
Department of Chemistry, Virginia Tech, Blacksburg, Virginia 24060, United States.
Recently photoinduced dynamic ligation in a metal-organic frameworks (MOFs) was reported, where a long-lived charge-transfer excited state (ca. 30 μs) featuring partial dissociation between the carboxylate linker and metal-based node was probed by time-resolved infrared (TRIR) spectroscopy. The study offers a new mechanistic perspective to evaluate the potential contribution from the excited state molecular configuration to the performance of MOF photocatalysts.
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