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http://dx.doi.org/10.1016/j.vaccine.2017.01.042 | DOI Listing |
Objective: .Aim: To investigate the pathomorphological changes in the terminal chorionic villi during COVID-19 in pregnant women.
Patients And Methods: Materials and Methods: A total of 123 placentas were studied in cases of live term births (groups І) and antenatal asphyxia (groups ІІ).
PLoS One
September 2025
Department of Orthopedic Surgery, Center for Shoulder and Elbow Surgery, Konkuk University School of Medicine, Seoul, Korea.
Purpose: We aimed to compare the effects of atelocollagen (AC) and individual growth factors on the expression of key molecular markers associated with tendon healing.
Methods: C2C12 myoblasts were cultured in Dulbecco's Modified Eagle Medium (DMEM) containing 5% fetal bovine serum (FBS) and treated with 1 nM or 10 nM of Atelocollagen (AC), bone morphogenetic protein-2 (BMP-2), transforming growth factor-beta 1 (TGF-β1), insulin-like growth factor-1 (IGF-1), or vascular endothelial growth factor (VEGF) for 5 days. After 5 days of treatment, cells were harvested from the culture medium, and Western blot analysis was performed to quantify the expression of phosphorylated extracellular signal-regulated kinase (p-ERK), Collagen type I (Col I), Collagen type Ⅲ (Col Ⅲ), and Tenascin C (TnC).
PLoS One
September 2025
Department of Pathology, Boston Children's Hospital, Harvard School of Medicine, Boston, Massachusetts, United States of America.
The Sudden Infant Death Syndrome (SIDS) is a major global health problem, with increased risk among socioeconomically disadvantaged populations. We propose SIDS, or a subset, is due to a defect in the brainstem serotonin system mediating cardiorespiratory integration and arousal. This defect impinges on homeostasis during a critical developmental period in infancy, especially in populations experiencing maternal and infantile stress, resulting in sleep-related sudden death.
View Article and Find Full Text PDFRadiat Environ Biophys
September 2025
Graduate School of Biomedical Sciences, Tokushima University, Tokushima, Japan.
Sodium orthovanadate (vanadate), a potent inhibitor of p53, has been shown in earlier work to alleviate total-body irradiation (TBI)-induced hematopoietic syndrome. However, as p53 plays a crucial role in normal spermatogenesis, its suppression may raise concerns about potential adverse effects on male reproductive function. In this study, we investigated whether vanadate exacerbates impairment of male fertility when administered for hematopoietic protection under TBI conditions.
View Article and Find Full Text PDFActa Obstet Gynecol Scand
September 2025
Unit of Gynecological Oncology, Department of Oncology, KU Leuven, Leuven, Belgium.
Introduction: Vulvovaginal cancer in pregnancy is rare. Limited data complicate decision-making and patient counseling. Our review, coupled with new case data, fills a current gap in the literature and provides practical insights.
View Article and Find Full Text PDF