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Sporting performance is often investigated through graphical observation of key technical variables that are representative of whole movements. The presence of differences between athletes in such variables has led to terms such as movement signatures being used. These signatures can be multivariate (multiple time-series observed concurrently), and also be composed of variables measured relative to different scales. Analytical techniques from areas of statistics such as Functional Data Analysis (FDA) present a practical alternative for analysing multivariate signatures. When applied to concurrent bivariate time-series multivariate functional principal components analysis (referred to as bivariate fPCA or bfPCA in this paper) has demonstrated preliminary application in biomechanical contexts. Despite this, given the infancy of bfPCA in sports biomechanics there are still necessary considerations for its use with non-conventional or complex bivariate structures. This paper focuses on the application of bfPCA to the force-angle graph in on-water rowing, which is a bivariate structure composed of variables with different units. A normalisation approach is proposed to investigate and standardise differences in variability between the two variables. The results of bfPCA applied to the non-normalised data and normalised data are then compared. Considerations and recommendations for the application of bfPCA in this context are also provided.
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http://dx.doi.org/10.1080/14763141.2017.1384050 | DOI Listing |
Int J Nanomedicine
September 2025
Department of Infectious Diseases, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, People's Republic of China.
The STING pathway has emerged as a therapeutic target in tumor immunotherapy due to its ability to induce interferon responses, enhance antigen presentation and activate T cells. Despite its therapeutic potential, STING pathway-based tumor immunotherapy has been limited by challenges in poor cellular delivery, rapid degradation of STING agonists, and potential systemic toxicity. Recently, advancements in nanotechnology have tried to overcome these limitations by providing platforms for more accurate and efficient targeted delivery of agonists, more moderate sustained STING pathway activation, and more efficient immune presentation and anti-tumor immune response.
View Article and Find Full Text PDFBeetroot ( L.) incorporation into cupcake formulations represents an innovative approach to developing functional bakery products that combine consumer appeal with enhanced nutritional value. This study investigated the incorporation of beetroot ( L.
View Article and Find Full Text PDFAlpha Psychiatry
August 2025
Department of Addictology, 1st Faculty of Medicine, Charles University and General University Hospital in Prague, 128 00 Prague, Czech Republic.
Objective: Information about the level of general personality functioning could provide benefits for tailoring substance use disorder (SUD) treatment. This study examined self-reported personality functioning among patients with SUD compared to the general population, gender specifics, and the psychometric properties of the Czech Level of Personality Functioning Scale-Self Report (LPFS-SR).
Methods: Two samples were used in this study.
Phys Chem Chem Phys
September 2025
School of Chemistry and Chemical Engineering, Nanjing University of Science and Technology, Nanjing, 210094, China.
To analyse the issues of high muzzle flame intensity and the easy migration of insensitive agents in conventional insensitive propellants, this study synthesizes modified nitrocellulose grafted with carboxymethyl potassium groups by a two-step process, starting from the molecular structure of nitrocellulose (NC), the principal component of propellants. First, the denitration reaction was performed to reduce part of the nitrate ester groups on the surface of NC to hydroxyl groups, followed by an etherification reaction to achieve directional grafting of carboxymethyl potassium groups. Compared with conventional flame retardant/insensitive systems based on nitrogen, phosphorus, or DBP (dibutyl phthalate), potassium-based functional groups exhibit superior thermal stability and environmental friendliness.
View Article and Find Full Text PDFSmall Methods
September 2025
The Research Institute for Advanced Manufacturing, and Department of Mechanical Engineering, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong SAR, 999077, China.
Nitrogen cycle is a fundamental biogeochemical loop existed for millions of years, which involves the transformation of nitrogen-containing chemicals in the environment. However, human activities, especially those since the Industrial Revolution, have significantly disrupted this balance, leading to environmental and energy challenges. Electrocatalysis nitrogen cycle (ENC) offers a promising alternative for the sustainable transformation of nitrogen compounds en route toward rebalancing, with reactions such as the electrocatalytic nitrogen reduction reaction (eNRR) and nitrate/nitrite reduction reaction (eNORR/eNORR) emerging as sustainable alternatives to the traditional Haber-Bosch process.
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