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http://dx.doi.org/10.21037/jtd.2017.06.80 | DOI Listing |
Neurol Med Chir (Tokyo)
September 2025
Department of Neurosurgery, Institute of Medicine, University of Tsukuba.
Early postoperative seizures, defined as occurring within 7 days after surgery, are a significant complication that occurs following neurosurgical procedures involving cerebral manipulation. As a result, short-term antiseizure medication is typically administered in Japan despite the lack of consensus regarding its prophylactic use. Perampanel hydrate, an α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor antagonist, was recently introduced in an intravenous formulation in Japan, providing new potential for early postoperative seizures prevention during the perioperative period.
View Article and Find Full Text PDFEpidemiol Serv Saude
September 2025
Universidade Federal de Brasília, Departamento de Saúde Coletiva, Brasília, DF, Brasil.
Objective: To evaluate factors associated with complications related to the use of peripherally inserted central venous catheters in children undergoing surgical procedures.
Methods: This was a case-control study, conducted in a public hospital in Sorocaba, with an emphasis on surgical procedures, between 2018 and 2022. Electronic medical records were used as a source of information.
Am J Emerg Med
August 2025
Medical Governance Research Institute, 2-12-13 -201 Takanawa, Minato, Tokyo 108-0074, Japan.
A previously healthy 40-year-old man presented to the emergency department with acute abdominal pain and repeated bilious vomiting that began the previous day and progressively worsened. On examination, he was afebrile and hemodynamically stable, with mild diffuse abdominal tenderness and no peritoneal signs. Laboratory studies showed leukocytosis with neutrophil predominance, an elevated C-reactive protein, and no eosinophilia.
View Article and Find Full Text PDFTheranostics
August 2025
Cancer Center, Renmin Hospital of Wuhan University, Wuhan, Hubei, 430060, China.
Hepatocellular carcinoma (HCC) causes a significant mortality burden worldwide. Radiotherapy (RT) is the primary locoregional treatment modality for HCC. However, the efficacy of RT in HCC is limited by tumor microenvironment (TME) hypoxia, immunosuppression, and extracellular matrix (ECM) stiffness.
View Article and Find Full Text PDFCureus
July 2025
Internal Medicine, Los Robles Regional Medical Center, Thousand Oaks, USA.
Hypercalcemia of malignancy is a common and life-threatening complication in cancer patients, typically seen in advanced breast cancer, multiple myeloma, and non-small-cell lung cancer. In contrast, it is rare in small-cell lung carcinoma (SCLC), where parathyroid hormone levels remain mostly within the normal range despite elevated calcium. We present a case of hypercalcemia in a patient with SCLC and discuss its clinical implications.
View Article and Find Full Text PDF