Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

A novel glucoside bletilloside A (1) was isolated from the tubers of Bletilla striata, together with seven known compounds (2-8). Their structures were determined on the basis of extensive spectroscopic analyses. All compounds were evaluated for the inhibition on NO production effects in RAW 264.7 macrophage cells, while militarine (4) and dactylorhin A (5) exhibited moderate inhibitory effects.

Download full-text PDF

Source
http://dx.doi.org/10.1080/10286020.2017.1339696DOI Listing

Publication Analysis

Top Keywords

bletilla striata
8
raw 2647
8
2647 macrophage
8
macrophage cells
8
chemical constituents
4
constituents bletilla
4
striata production
4
production suppression
4
suppression raw
4
cells novel
4

Similar Publications

Self-pumping Janus nanofiber membrane with pH monitoring capability, integrated with a drug-loaded fast-dissolving layer for enhanced chronic wound healing.

Colloids Surf B Biointerfaces

September 2025

State Key Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China. Electronic address:

The emergence of antimicrobial resistance poses significant challenges in conventional antibiotic treatments for chronic wound infections, highlighting an urgent need for alternative therapeutic strategies. To address this issue, we developed a multifunctional electrospun nanofiber dressing co-loaded with anthocyanin (ATH) and asiaticoside (AS) that possesses antimicrobial activity. The tri-layer dressing contains three functional components: a hydrophilic polyacrylonitrile-anthocyanin (PAN-ATH) layer for pH monitoring, a hydrophobic polycaprolactone (PCL) layer for exudate management, and a water-soluble pullulan-Bletilla striata polysaccharide-asiaticoside (PUL-BSP-AS) layer.

View Article and Find Full Text PDF

Wound healing is often hindered by bacterial infection, oxidative stress, and bleeding. Traditional dressings cannot simultaneously regulate multiple microenvironments. To address the shortcomings of traditional dressings, this study constructed a dual-network photothermal responsive multifunctional hydrogel OBCTCu based on four natural ingredients, including Bletilla striata polysaccharide (BSP), chitosan (CS), tannic acid (TA), and Cu.

View Article and Find Full Text PDF

Peptic ulcer (PU) is characterized by inflammation, necrosis, and erosion of the gastrointestinal mucosa caused by various pathogenic factors, leading to ulcer formation. The stomach and duodenum are the most commonly affected sites. , a traditional Chinese medicinal herb, contains diverse chemical constituents and exhibits multiple pharmacological effects.

View Article and Find Full Text PDF

Natural multi-active nanoparticles integrated biological hydrogel microcarriers for wound healing.

J Nanobiotechnology

August 2025

Department of Rheumatology and Immunology, School of Biological Science and Medical Engineering, Nanjing Drum Tower Hospital, Southeast University, Nanjing, 210096, China.

Bioactive substance-integrated hydrogels have demonstrated efficacy in diabetic wound treatment. However, challenges remain in identifying naturally derived, multifunctional active substances capable of addressing the complex pathophysiology of wounds, as well as in tailoring hydrogels to enhance their suitability for wound applications. Here, we present a novel biological hydrogel microcarrier system by integrating Bletilla striata-derived nanoparticles (PdNPs) and polydopamine nanozymes (PDAs) into a hyaluronic acid-methacrylate (HAMA) hydrogel.

View Article and Find Full Text PDF

We assessed the genetic diversity and population structure of the protected orchid across 18 wild populations in southwestern China. Eight pairs of simple sequence repeat (SSR) molecular markers were employed for its genetic diversity and population structure analyses, while the optimized Maxent model was utilized to predict changes in the habitat distribution under historical conditions and three future climate scenarios (SSP126, SSP245, and SSP585) with 141 natural distribution data and 19 climatic factors. The results revealed an average number of alleles () of 3.

View Article and Find Full Text PDF