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Objective: The purpose of this study was to determine if wellness programs are likely to produce an adverse impact in various protected groups and to determine what features of the program may contribute to adverse impact.
Methods: Using a nationally representative sample of US adults, we examined the proportions of protected groups that would be expected to encounter adverse impact using various health factors such as weight, blood pressure, and cholesterol levels.
Results: The results of this study indicate that disincentive-based programs pose a high risk of differentially selecting protected groups into program categories. This is especially true for members of multiple protected classes.
Conclusions: We suggest organizations carefully consider both the type of program and the health factors incorporated into their wellness efforts and use incentives rather than disincentives to encourage health promotion.
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http://dx.doi.org/10.1097/JOM.0000000000000940 | DOI Listing |
BMC Pediatr
September 2025
Department of Neonatology, Zhangzhou Affiliated Hospital of Fujian Medical University, Zhangzhou, Fujian, China.
Background: Red blood cell (RBC) transfusion is a common intervention for anemia in preterm infants; however, its association with bronchopulmonary dysplasia (BPD) remains debated. While biological mechanisms suggest potential harm, the clinical impact of transfusion frequency on BPD incidence and severity remains unclear.
Objective: To investigate whether RBC transfusion frequency is independently associated with the risk and severity of BPD in preterm infants born before 32 weeks of gestation.
Eye (Lond)
September 2025
Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, ON, Canada.
Background: Blepharitis, meibomian gland dysfunction (MGD), and chalazia are common disorders impacting quality of life. This population-based, pharmacovigilance study aims to identify systemic drugs disproportionately linked to these disorders.
Methods: Data from the Food and Drug Administration Adverse Event Reporting System (FAERS) were analysed (Q4 2003 to Q2 2024).
Eur J Clin Pharmacol
September 2025
Department of Forensic Pathology, West China School of Basic Medical Sciences & Forensic Medicine, Sichuan University, Chengdu, 610041, China.
Background And Objective: While current clinical guidelines generally advocate for beta-blocker therapy following acute myocardial infarction (AMI), conflicting findings have surfaced through large-scale observational studies and meta-analyses. We conducted this systematic review and meta-analysis of published observational studies to quantify the long-term therapeutic impact of beta-blocker across heterogeneous AMI populations.
Methods: We conducted comprehensive searches of the PubMed, Embase, Cochrane, and Web of Science databases for articles published from 2000 to 2025 that examine the link between beta-blocker therapy and clinical outcomes (last search update: March 1, 2025).
Nat Commun
September 2025
CReATe Fertility Centre, Toronto, ON, Canada.
Cannabis consumption and legalization is increasing globally, raising concerns about its impact on fertility. In humans, we previously demonstrated that tetrahydrocannabinol (THC) and its metabolites reach the ovarian follicle. An extensive body of literature describes THC's impact on sperm, however no such studies have determined its effects on the oocyte.
View Article and Find Full Text PDFProc Biol Sci
September 2025
Department of Wildlife, Fish and Environmental Studies, Swedish University of Agricultural Sciences, 901 83 Umeå, Västerbotten County, Sweden.
Pharmaceutical contaminants reaching natural aquatic ecosystems can affect fish behaviour, modifying activity patterns, foraging behaviour and antipredator responses. While laboratory-based studies can offer key insights, assessing the ecological relevance of these findings requires field-based approaches. Therefore, we examined the effects of oxazepam, a widely prescribed anxiolytic drug, on the behaviour of a cyprinid fish (the common roach, ) in the wild, combining slow-release exposure implants with continuous tracking via acoustic telemetry.
View Article and Find Full Text PDF