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Purpose: The purpose of this study was to determine the vocal fold structural and vibratory symmetries that are important to vocal function and voice quality in a simulated paramedian vocal fold paralysis.
Method: A computational kinematic speech production model was used to simulate an exemplar "voice" on the basis of asymmetric settings of parameters controlling glottal configuration. These parameters were then altered individually to determine their effect on maximum flow declination rate, spectral slope, cepstral peak prominence, harmonics-to-noise ratio, and perceived voice quality.
Results: Asymmetry of each of the 5 vocal fold parameters influenced vocal function and voice quality; measured change was greatest for adduction and bulging. Increasing the symmetry of all parameters improved voice, and the best voice occurred with overcorrection of adduction, followed by bulging, nodal point ratio, starting phase, and amplitude of vibration.
Conclusions: Although vocal process adduction and edge bulging asymmetries are most influential in voice quality for simulated vocal fold motion impairment, amplitude of vibration and starting phase asymmetries are also perceptually important. These findings are consistent with the current surgical approach to vocal fold motion impairment, where goals include medializing the vocal process and straightening concave edges. The results also explain many of the residual postoperative voice limitations.
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http://dx.doi.org/10.1044/2016_JSLHR-S-16-0076 | DOI Listing |
J Acoust Soc Am
September 2025
Department of Head and Neck Surgery, University of California, Los Angeles, 31-24 Rehab Center, 1000 Veteran Avenue, Los Angeles, California 90095-1794, USA.
The goal of this study was to understand the interaction between the voice source spectral shape, formant tuning, and fundamental frequency in determining the vocal tract contribution to vocal intensity. Computational voice simulations were performed with parametric variations in both vocal fold and vocal tract configurations. The vocal tract contribution to vocal intensity was quantified as the difference in the A-weighted sound pressure level between the radiated sound pressure and the sound pressure at the glottis.
View Article and Find Full Text PDFJ Voice
September 2025
Department of Speech and Language Therapy, Faculty of Health Sciences, Hacettepe University, Ankara, Turkey. Electronic address:
Objectives: In individuals over 65, age is an essential factor in voice changes. Acoustic and aerodynamic norms guide clinicians in interpreting clinical voice assessment results. This study aimed to present aerodynamic-acoustic voice measurements in older individuals with no voice complaints.
View Article and Find Full Text PDFPLoS One
September 2025
Department of Otolaryngology-Head and Neck Surgery, Nihon University School of Medicine, Tokyo, Japan.
Glottic insufficiency results from impaired vocal fold contact, leading to a gap between the folds and manifesting as hoarseness and respiratory difficulties. Vocal folds injection is a commonly utilized therapeutic approach to rectify this gap by augmenting vocal folds volume; however, the optimal injectable material remains undetermined. Dedifferentiated fat cells (DFATs), derived from mature adipocytes, exhibit robust proliferative capacity and multipotency, establishing them as potential candidates for treating glottic insufficiency.
View Article and Find Full Text PDFLaryngoscope
September 2025
UAB Voice Center, Department of Otolaryngology-Head and Neck Surgery, Heersink School of Medicine, Birmingham, Alabama, USA.
Objectives: To examine factors that direct decisions in the treatment of glottic insufficiency and propose a paradigm that may assist in treatment decision-making in glottic insufficiency.
Methods: A retrospective chart review was completed of 73 patients with vocal fold atrophy, presbyphonia, or vocal fold motion impairment, including diagnosis, Voice Handicap Index-10 (VHI-10), Voice Problem Impact Scales (VPIS), Glottal Function Index (GFI), Eating Assessment Tool-10 (EAT-10), Consensus Auditory Perceptual Analysis of Voice (CAPE-V), glottal gap size, stimulability, treatment decisions, and outcomes. Univariate and multivariate logistic regression analyses were performed to identify which variables predicted initial treatment recommendation.
Trop Doct
September 2025
Professor and Head, Department of Dermatology, Venereology and Leprosy, King George's Medical University, Lucknow, Uttar Pradesh, India.
A 56-year old immuno-competent male from a non-endemic region in India presented with progressive weight loss, hoarseness of voice and widespread cutaneous lesions, including leonine facies, genital nodules and diffuse scaling. Magnetic resonance imaging of the neck revealed oedematous thickening of the false vocal cords, epiglottis and aryepiglottic folds, suggesting laryngeal involvement. All routine investigations were normal.
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