Immediate or Delayed Nephrectomy in Patients With Metastatic Renal Cancer Who Are Receiving Targeted Agents: Is the Analysis at Risk for Guarantee-Time Bias?

J Clin Oncol

Consuelo Buttigliero and Marcello Tucci, University of Turin, San Luigi Gonzaga Hospital, Orbassano, Turin, Italy; and Francesca Vignani and Massimo Di Maio, University of Turin, Mauriziano Hospital, Turin, Italy.

Published: April 2017


Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

Download full-text PDF

Source
http://dx.doi.org/10.1200/JCO.2016.69.3580DOI Listing

Publication Analysis

Top Keywords

delayed nephrectomy
4
nephrectomy patients
4
patients metastatic
4
metastatic renal
4
renal cancer
4
cancer receiving
4
receiving targeted
4
targeted agents
4
agents analysis
4
analysis risk
4

Similar Publications

Adrenal capillary hemangiomas are an extremely rare tumor type, and no previous studies have described their features using dynamic contrast-enhanced computed tomography. We report the case of a 65-year-old male patient with a history of right partial nephrectomy for renal clear cell carcinoma. During follow-up, computed tomography scans revealed growth of a right adrenal nodule.

View Article and Find Full Text PDF

Purpose: Immune checkpoint blockade (ICB) has transformed outcomes for patients with metastatic renal cell carcinoma (mRCC) and has impacted the timing and use of cytoreductive nephrectomy (CN). As ICB responses vary, we evaluated whether radiographic and radiomic biomarkers were associated with clinical and pathological outcomes.

Methods: This retrospective cohort study included ICB-treated mRCC patients without upfront CN.

View Article and Find Full Text PDF

Renal, bladder and prostate cancer surgery outcomes with respect to team familiarity.

BJU Int

September 2025

Division of Clinical Medicine, School of Medicine & Population Health, University of Sheffield, Sheffield, UK.

Objectives: To investigate outcomes in urological oncology according to team membership and familiarity.

Subjects/patients: We assessed peri-operative times, lengths of stay and re-admission rates in all patients undergoing surgery for prostate, bladder and kidney cancer at Sheffield Teaching Hospitals from 2021 to September 2024. Our analysis was performed with respect to staff pairs and a validated familiarity score (FS) derived using seven team members.

View Article and Find Full Text PDF

Laparoscopic Resection of a Rare Retroperitoneal Dermoid Cyst in a 78-Year-Old Woman: A Case Report.

Am J Case Rep

September 2025

Department of Urology, The Affiliated Suzhou Hospital of Nanjing Medical University, Suzhou Municipal Hospital, Gusu School, Nanjing Medical University, Suzhou, Jiangsu, China.

BACKGROUND Primary retroperitoneal tumors (PRTs) are uncommon, with retroperitoneal dermoid cysts being particularly rare. The cystic cavity of mature cystic teratomas (dermoid cysts) is lined with squamous epithelium and primarily filled with sebaceous material. These lesions often lack specific symptoms, leading to delayed diagnosis.

View Article and Find Full Text PDF

Horseshoe kidney (HSK) complicated with renal parenchymal squamous cell carcinoma (RSCC) is exceedingly rare and clinically insidious. Owing to the absence of pathognomonic symptoms or imaging hallmarks, the malignancy is frequently obscured by coexistent renal calculi, hydronephrosis, or infection, resulting in formidable diagnostic challenges, missed diagnoses, and consequently delayed treatment. We report a 60-year-old man who presented with HSK, left renal calculi, and hydronephrosis.

View Article and Find Full Text PDF