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Frequency conversion with nonlinear electronic components, a common approach for signal processing required in various communication applications, has found its operation bandwidth bottleneck due to the limited carrier mobility of the traditional materials. Meanwhile, fiber-optics communications are playing a significant role in communication services due to their excellent signal transmission properties. However, the transmitted optical signals had to be converted to electrical signals with photodetectors before frequency conversion was performed through conventional electronic devices, which make this conversion system very complex and costly. Hence, to develop a compact device that can achieve the photodetection and frequency conversion functions simultaneously is critical and significative. Here, we have proposed a novel concept for frequency conversion and demonstrated a nonlinear graphene photodetector based frequency converter that performs frequency conversion from optical signals directly. With this new concept, a frequency doubling signal at 4 GHz was obtained from a 2 GHz intensity-modulated optical signal. Moreover, using a 10 MHz intensity-modulated optical signal and another 3 GHz intensity-modulated optical signal, we show the frequency up-conversion to 3 ± 0.01 GHz. In particular, the frequency down-conversion to 100 MHz was achieved successfully by using a 2 GHz intensity-modulated optical signal and another 2.1 GHz intensity-modulated optical signal. Considering the broadband optical absorption, strong saturable absorption, high carrier mobility, and short photogenerated carrier lifetime of the graphene material, graphene photodetectors have the potential to achieve the frequency conversion of millimeter-wave band, which will open promising prospects in the domain of microwave photonics for next-gen communication systems.
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http://dx.doi.org/10.1039/c6nr08964j | DOI Listing |
PLoS Med
September 2025
University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States of America.
Background: Oral emtricitabine/tenofovir disoproxil fumarate (F/TDF) preexposure prophylaxis (PrEP) effectiveness against HIV acquisition highly depends on adherence. For men who have sex with men, a dosing study in the United States (US) population defined clinically meaningful tenofovir diphosphate (TFV-DP) thresholds in dried blood spots (DBS) based on the rounded 25th percentile for 2, 4, and 7 doses/week as 350, 700, and 1,250 fmol/punch. However, divergent efficacy results in the first generation randomized clinical trials of F/TDF PrEP among African women led to several hypotheses to question whether the pharmacology and adherence requirement for oral F/TDF PrEP may be different in cisgender women compared to what is already established for men.
View Article and Find Full Text PDFNat Commun
September 2025
School of Materials Science and Engineering, Nanyang Technological University, Singapore, Singapore.
The photovoltaic performance of CuZnSn(S,Se) is limited by open-circuit voltage losses (ΔV) in the radiative (ΔV) and non-radiative (ΔV) limits, due to sub-bandgap absorption and deep defects, respectively. Recently, several devices with power conversion efficiencies approaching 15% have been reported, prompting renewed interest in the possibility that the key performance-limiting factors have been addressed. In this work, we analyze the sources of ΔV in these devices and offer directions for future research.
View Article and Find Full Text PDFJ Child Neurol
September 2025
Department of Epidemiology and Environmental Health, State University of New York at Buffalo, Buffalo, NY, USA.
Mass psychogenic illness (MPI), also known as mass sociogenic illness, is a functional neurologic symptom disorder affecting multiple people simultaneously. This study presents a pediatric MPI outbreak involving abrupt-onset tics in LeRoy, NY, during 2011-2012. The analysis provides diagnostic evidence and highlights challenges with diagnosing MPI.
View Article and Find Full Text PDFRev Sci Instrum
September 2025
Department of Nuclear Engineering, University of California, Berkeley, Berkeley, California 94720, USA.
Current and future searches for dark matter axions, based on their resonant conversion to photons in a magnetic field, span many orders of magnitude. A major impediment to designing resonators at the high end of this range, 5 GHz and above, is the proliferation of TE modes, which overwhelm and hybridize with the TM010 mode to which the axion couples, making the search impossible. We demonstrate that a photonic bandgap structure can be designed that completely suppresses the TE spectrum, even reducing the number of lattice periods to two or one and violating perfect lattice symmetry.
View Article and Find Full Text PDFVet Anim Sci
September 2025
Department of Animal Science, School of Agriculture Shiraz University, Shiraz 71441-65186, Iran.
The increasing frequency of droughts and water scarcity has intensified interest in drought-tolerant plants and their by-products as sustainable feed alternatives for ruminants. This study assessed the partial replacement of alfalfa hay (AH) with camelina straw (CS) at 120 (CS12) and 240 (CS24) g/kg of DM in diets of Grey Shirazi lambs ( = 24, average body weight = 22.7 ± 1.
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