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http://dx.doi.org/10.1177/0883073816681353 | DOI Listing |
J Neuroeng Rehabil
September 2025
Institute for Neuromodulation and Neurotechnology, University Hospital and University of Tübingen, 72076, Tübingen, Germany.
Innovative technology allows for personalization of stimulation frequency in dual-site deep brain stimulation (DBS), offering promise for challenging symptoms in advanced Parkinson's disease (PD), particularly freezing of gait (FoG). Early results suggest that combining standard subthalamic nucleus (STN) stimulation with substantia nigra pars reticulata (SNr) stimulation may improve FoG outcomes. However, patient response and the optimal SNr stimulation frequency vary.
View Article and Find Full Text PDFMol Psychiatry
September 2025
Department of Psychiatry and Behavioral Neuroscience, University of Chicago, Chicago, IL, USA.
Stimulant Use Disorder (StUD) is a pervasive and extremely dangerous form of addiction for which there are currently no approved medications. Discovering treatments will require a deep understanding of the neural mechanisms underlying the behavioral effects of stimulant drugs. A major target is the mesocorticolimbic system.
View Article and Find Full Text PDFMed Eng Phys
October 2025
Biomedical Device Technology, Istanbul Aydın University, Istanbul, 34093, Istanbul, Turkey. Electronic address:
Deep learning approaches have improved disease diagnosis efficiency. However, AI-based decision systems lack sufficient transparency and interpretability. This study aims to enhance the explainability and training performance of deep learning models using explainable artificial intelligence (XAI) techniques for brain tumor detection.
View Article and Find Full Text PDFAJNR Am J Neuroradiol
September 2025
From the Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America (J.S.S., B.M., S.H., A.H., J.S.), and Department of Aerospace Engineering, Indian Institute of Technology Madras, Chennai, Tamil Nadu, India (H.S.).
Background And Purpose: The choroid of the eye is a rare site for metastatic tumor spread, and as small lesions on the periphery of brain MRI studies, these choroidal metastases are often missed. To improve their detection, we aimed to use artificial intelligence to distinguish between brain MRI scans containing normal orbits and choroidal metastases.
Materials And Methods: We present a novel hierarchical deep learning framework for sequential cropping and classification on brain MRI images to detect choroidal metastases.
J Neural Eng
September 2025
Eindhoven University of Technology, De Rondom 70, Eindhoven, 5612 AP, NETHERLANDS.
Transcranial temporal interference stimulation (tTIS) has recently emerged as a non-invasive neuromodulation method aimed at reaching deeper brain regions than conventional techniques. However, many questions about its effects remain, requiring further experimental studies. This review consolidates the experimental literature on tTIS's effects in the human brain, clarifies existing evidence, identifies knowledge gaps, and proposes future research directions to evaluate its potential.
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