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Causal Bayes nets capture many aspects of causal thinking that set them apart from purely associative reasoning. However, some central properties of this normative theory routinely violated. In tasks requiring an understanding of explaining away and screening off, subjects often deviate from these principles and manifest the operation of an associative bias that we refer to as the rich-get-richer principle. This research focuses on these two failures comparing tasks in which causal scenarios are merely described (via verbal statements of the causal relations) versus experienced (via samples of data that manifest the intervariable correlations implied by the causal relations). Our key finding is that we obtained stronger deviations from normative predictions in the described conditions that highlight the instructed causal model compared to those that presented data. This counterintuitive finding indicate that a theory of causal reasoning and learning needs to integrate normative principles with biases people hold about causal relations.
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http://dx.doi.org/10.3758/s13421-016-0662-3 | DOI Listing |
Cereb Cortex
August 2025
Brain and Cognition, KU Leuven, Tiensestraat 102, 3000 Leuven, Belgium.
Centro-parietal electroencephalogram signals (centro-parietal positivity and error positivity) correlate with the reported level of confidence. According to recent computational work these signals reflect evidence which feeds into the computation of confidence, not directly confidence. To test this prediction, we causally manipulated prior beliefs to selectively affect confidence, while leaving objective task performance unaffected.
View Article and Find Full Text PDFProc Natl Acad Sci U S A
September 2025
Department of Medicine, Institute for Transformative Molecular Medicine, Case Western Reserve University School of Medicine, Cleveland, OH 44106.
The β-adrenergic receptor (βAR), a prototype G protein-coupled receptor, controls cardiopulmonary function underpinning O delivery. Abundance of the βAR is canonically regulated by G protein-coupled receptor kinases and β-arrestins, but neither controls constitutive receptor levels, which are dependent on ambient O. Basal βAR expression is instead regulated by the prolyl hydroxylase/pVHL-E3 ubiquitin ligase system, explaining O responsivity.
View Article and Find Full Text PDFJAMA Netw Open
September 2025
Perelman School of Medicine, University of Pennsylvania, Philadelphia.
Importance: As obesity rates rise in the US, managing associated metabolic comorbidities presents a growing burden to the health care system. While bariatric surgery has shown promise in mitigating established metabolic conditions, no large studies have quantified the risk of developing major obesity-related comorbidities after bariatric surgery.
Objective: To identify common metabolic phenotypes for patients eligible for bariatric surgery and to estimate crude and adjusted incidence rates of additional metabolic comorbidities associated with bariatric surgery compared with weight management program (WMP) alone.
JAMA Netw Open
September 2025
Department of Population Health Sciences, University of Utah School of Medicine, Salt Lake City.
Importance: Advances in diagnostics have enabled the detection of more gastrointestinal pathogens, but misuse of diagnostics can lead to inappropriate antibiotic use and excess financial burdens. Ensuring appropriate use of diagnostics is crucial for optimizing patient care and promoting stewardship of health care resources.
Objective: To elicit parents' and clinicians' perspectives on expectations for care of pediatric diarrhea with a focus on diagnostic testing and to evaluate the potential for an electronic clinical decision support tool (ECDST) to improve appropriate use of diagnostics.
Age Ageing
August 2025
Department of Nursing Health Services Research, Graduate School of Health Care Sciences, Institute of Science Tokyo, Yushima, Bunkyo-ku, Tokyo, Japan.
Background: Little is known about how ambulatory care sensitive condition (ACSC)-related readmissions can be reduced in acute care settings.
Objective: This study examined the association between transitional care for hospitalised older patients with ACSC and ACSC-related readmissions.
Methods: This retrospective observational cohort study included patients aged 65 years and older admitted with ACSC as the primary diagnosis from 1 April 2022 to 31 January 2023, using linked data from the Diagnosis Procedure Combination and the medical functions of the hospital beds database.