98%
921
2 minutes
20
Torulaspora delbrueckii can improve wine aroma complexity, but its impact on wine quality is still far from being satisfactory at the winery level, mainly because it is easily replaced by S. cerevisiae yeasts during must fermentation. New T. delbrueckii killer strains were selected to overcome this problem. These strains killed S. cerevisiae yeasts and dominated fermentation better than T. delbrueckii non-killer strains when they were single-inoculated into crushed red grape must. All the T. delbrueckii wines, but none of the S. cerevisiae wines, underwent malolactic fermentation. Putative lactic acid bacteria were always found in the T. delbrueckii wines, but none or very few in the S. cerevisiae wines. Malic acid degradation was the greatest in the wines inoculated with the killer strains, and these strains reached the greatest dominance ratios and had the slowest fermentation kinetics. The T. delbrueckii wines had dried-fruit/pastry aromas, but low intensities of fresh-fruit aromas. The aroma differences between the T. delbrueckii and the S. cerevisiae wines can be explained by the differences that were found in the amounts of some fruity aroma compounds such as isoamyl acetate, ethyl hexanoate, ethyl octanoate, and some lactones. This T. delbrueckii effect significantly raised the organoleptic quality scores of full-bodied Cabernet-Sauvignon red wines inoculated with the killer strains. In particular, these wines were judged as having excellent aroma complexity, mouth-feel, and sweetness.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1016/j.ijfoodmicro.2016.09.029 | DOI Listing |
Biomed Eng Lett
September 2025
Department of Electrical & Biological Physics, Kwangwoon University, Seoul, 01897 Republic of Korea.
Purpose: This study investigates the antibacterial and anticancer activity of previously reported iron oxide (FeO)-based nanoparticles (NPs) conjugated with chlorin e6 and folic acid (FCF) in photodynamic therapy (PDT) using a human bladder cancer (BC) (T-24) cell line and three bacterial strains.
Method: To investigate the potential applicability of the synthesized NPs as therapeutic agents for image-based photodynamic BC therapy, their photodynamic anticancer activity was analyzed and the mechanisms of cell death in T-24 cells treated with these NPs were assessed qualitatively and quantitatively through atomic absorption spectroscopy, fluorescence imaging, and transmission electron microscopy.
Results: The effective localization of FCF NPs in T-24 cells were confirmed, validating their excellent cellular fluorescence and magnetic resonance imaging capabilities.
J Int AIDS Soc
August 2025
U.S. Military HIV Research Program, CIDR, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.
Introduction: Cases of spontaneous control of HIV-1 can help define strategies to induce remission. Since the identification of viral control in the absence of treatment typically occurs after a prolonged period post-HIV-1 diagnosis, our knowledge of the early events after HIV-1 acquisition that led to viral control is limited.
Methods: The RV217 prospective cohort enrolled 2276 participants in East Africa (Kenya, Uganda, Tanzania) and Thailand between 2009 and 2015.
Front Immunol
August 2025
David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, United States.
Introduction: Numerous pre-vaccination factors are known to be associated with differential responses to influenza vaccination, including age, prior infection, vaccination history, immune cell frequencies, and transcriptomic profiles. However, plasma chemokines and cytokines are relatively unexplored. Given that older individuals have generally higher levels of inflammatory molecules in circulation, termed inflammaging, and also respond poorly to vaccination, plasma immune profiles likely play a role in effective response to influenza vaccination.
View Article and Find Full Text PDFVet Pathol
August 2025
Department of Veterinary Medicine and Animal Sciences, University of Milan, Lodi, Italy.
Immunodeficient mouse strains are widely used in several fields of biomedical research. Despite that, no standardized system for evaluating immunodeficiency in mice currently exists, and an unbiased comparison of various immunodeficient mouse strains is difficult. The aim of our study was to develop a standardized multi-disciplinary protocol for the morpho-phenotypical assessment of immunodeficient mouse models.
View Article and Find Full Text PDFFront Cell Infect Microbiol
August 2025
College of Animal Husbandry and Veterinary Medicine, Southwest Minzu University, Chengdu, China.
Mycobacteria pose significant global health burdens, with causing tuberculosis-a leading infectious killer claiming over 1.25 million lives annually-and NTM driving pulmonary and ulcerative infections, particularly in immunocompromised populations. Autophagy, a conserved cellular degradation pathway, serves as a critical mechanism of host defense against mycobacteria by delivering bacteria to the lysosome.
View Article and Find Full Text PDF