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Purpose: The aim of this study was to assess the kinematics of arthritic knees prior to TKA. The hypothesis was that the arthritic knee follows distinct patterns with regard to deformity in coronal plane as it flexes from extended position.
Method: Data from 585 consecutive arthritic knees that had undergone TKA using two non-image-based navigation systems were included in the study. Coronal plane alignment given by the femoro-tibial mechanical angle (FTMA) was recorded in extension, 30°, 60°, 90° and maximum flexion prior to making any bony cuts or ligamentous releases.
Results: Complete data were available for 512 (87.5 %) of arthritic knees. It was found that pre-implant arthritic knees behaved in different distinct patterns from full extension to 90° flexion. These patterns in FTMA from extension through to 90° of flexion were classified into 4 major types (1, 2, 3, and 4) and 8 subgroups (1A, 1B, 2A, 2B, 3, 4A, 4B, 4C) for varus and valgus knees. Beyond 90° of flexion, there were no distinct or consistent patterns. There were differences between varus and valgus knee deformities not only in overall numbers (73.8 % varus vs. 21.1 % valgus) but also in kinematic behaviour. Only 14.1 % of total knees had a consistent deformity (Type 1A) which remained the same throughout the range of flexion. 14.1 % knees actually become opposite deformity as the knee flexes; thus, varus becomes valgus and valgus becomes varus as the knee flexes (Type 3 and 4C).
Conclusion: This study has observed and categorised distinct patterns which arthritic knees follow in the coronal plane as it flexes. This dynamic change during flexion will have bearing on collateral releases that are traditionally done based on deformity in extension or 90° flexion mainly. This may be the underlying cause of flexion instability especially for Types 3 and 4C knees if collateral soft tissue release is done based on deformity in extension. Full significance of this remains unknown and will need further investigation.
Level Of Evidence: III.
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http://dx.doi.org/10.1007/s00167-016-4338-0 | DOI Listing |
J Orthop
December 2025
Department of Orthopaedic Surgery and Rehabilitation, Loyola University Medical Center, Maywood, IL, USA.
Background: Kinematic alignment (KA) in total knee arthroplasty (TKA) aims to restore natural knee kinematics by aligning components to the patient's pre-arthritic anatomy, unlike mechanical alignment (MA), which prioritizes the mechanical axis. Proper prosthesis sizing is essential for optimizing knee kinematics, yet most systems are designed around a MA philosophy, potentially affecting sizing when utilizing a KA philosophy. This study investigated whether intrinsic differences between kinematic and mechanical alignment techniques lead to discrepancies in femoral and tibial prosthesis sizing in primary TKA.
View Article and Find Full Text PDFBMC Musculoskelet Disord
September 2025
Department of Rehabilitation Assessment, Rehabilitation Hospital Affilated to Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, China.
Background: A single substantial clinical benefit (SCB) value for the Simplified Chinese Lower Extremity Functional Scale (SC-LEFS) that can be applied to those with lower extremity musculoskeletal injuries is available. However, unique SCB values defined by specific body region and symptom duration may enhance the precision of the SC-LEFS in clinical assessments.
Methods: This study aim to determine unique SCB values for the SC-LEFS based on symptom duration and body region.
Sci Rep
September 2025
Department of Therapeutic Chemistry, National Research Centre, 33 El-Bohouth St., Dokki, Cairo, 12622, Egypt.
Gouty arthritis (GA) is an inflammatory arthritic disorder that is characterized by intense, acute inflammatory responses, such as synovitis and arthritis that occur due to articular deposition of monosodium urate (MSU) crystals. This study has compared the therapeutic potentials of either Berberine (BERB) or Paracetamol (Para) on MSU-induced inflammation in rat model of Gouty arthritis (GA). GA was induced by "intra-articular" injection of MSU suspension (20 mg/ml) inside the knee joint of the rat's right limb.
View Article and Find Full Text PDFJ Orthop Surg Res
August 2025
Upper Limb Unit, Wrightington Hospital, Wigan and Leigh Teaching Hospitals NHS Foundation Trust, Wrightington, Wigan, UK.
Background: Total elbow replacement (TER) is an established treatment for the painful arthritic elbow; however, TER has higher failure rates than other joint replacements, such as hip and knee replacement. Understanding the prognostic factors associated with failure of TER is essential for informed decision-making between patients and clinicians, patient selection, and service planning. The aim of this study is to explore the views of patients and healthcare professionals on which potential prognostic factors should be investigated in relation to TER failure.
View Article and Find Full Text PDFJ Bone Joint Surg Am
August 2025
Commons Clinic, Long Beach, California.
Background: There is no foundational classification that 3-dimensionally characterizes arthritic anatomy to preoperatively plan and postoperatively evaluate total knee arthroplasty (TKA). With the advent of computed tomography (CT) as a preoperative planning tool, the purpose of this study was to morphologically classify pre-TKA anatomy across coronal, axial, and sagittal planes to identify outlier phenotypes and establish a foundation for future philosophical, technical, and technological strategies.
Methods: A cross-sectional analysis was conducted using 1,352 pre-TKA lower-extremity CT scans collected from a database at a single multicenter referral center.