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http://dx.doi.org/10.1021/acs.jpca.6b09344 | DOI Listing |
Medicina (Kaunas)
February 2025
Department of Physical Therapy, Gachon University, Incheon 21936, Republic of Korea.
: Weight-bearing activities exacerbate pain and fatigue in functional flat foot, with uphill walking presenting additional challenges due to increased external loads. The current study investigates whether 3D-printed customized arch-support insoles can enhance gait variables and ankle alignment during uphill walking. : Twenty healthy young adults, divided into two groups (normal foot condition (control, = 10), functional flat foot (FF, = 10)), walked on a treadmill at a 10% incline under two conditions: wearing shoes alone (shoe) or wearing shoes with 3D-printed customized arch-support insoles (SI).
View Article and Find Full Text PDFAdv Colloid Interface Sci
May 2025
School of Chemistry and Chemical Engineering, Yangzhou University, Yangzhou, 225002, Jiangsu, PR China; State Key Laboratory of Coordination Chemistry, Nanjing University, Nanjing 210023, PR China. Electronic address:
Covalent Organic Frameworks (COFs) are characterized by high thermochemical stability, low backbone density, well-controlled physical and chemical properties, large specific surface volume and porosity, permanently open pore structure, and various synthesis strategies. These remarkable attributes confer COFs with significant potential for a myriad of applications ranging from catalysis technology, gas separation and storage, optoelectronic materials, environmental and energy sciences, and biomedical development. There are many synthetic design methods for COF materials, and dynamic covalent chemistry is the scientific basis of COF materials-oriented design, which gives the error correction ability of the covalent assembly process, and is the key to obtaining crystallization and stability at the same time.
View Article and Find Full Text PDFSmall
December 2024
Key Laboratory of Radiation Physics & Technology, Ministry of Education, College of Chemistry, Sichuan University, Chengdu, 610064, China.
The stability of covalent organic frameworks (COFs) is crucial for their applications in demanding environments. However, increasing the stability of COFs often comes with challenges such as higher synthesis difficulty, lower crystal quality, and reduced controllability during synthesis, making it difficult to regulate dimensions and morphology, thereby impacting the processing and shaping of stable COFs. Herein, the study presents a novel confined polymerization approach guided by hydrogen bonding preassembly to synthesize a soluble and stable COF featuring β-ketoenamine linkage.
View Article and Find Full Text PDFTalanta
December 2024
Hebei Key Laboratory of Photoelectric Control on Surface and Interface, College of Science, Hebei University of Science and Technology, Shijiazhuang, 050018, China. Electronic address:
Accurate and sensitive detection of amyloid-β 42 oligomer (Aβ42O) is of great significance for early diagnosis of Alzheimer's disease (AD). Herein, a signal on-off ratiometric electrochemical immunosensor was developed for highly selective and quantitative determination of Aβ42O by using novel covalent organic frameworks (COFs) composites as the sensing platform. This immunosensor produced two independent electrochemical signals from the [Fe(CN)] and methylene blue (MB) probes at different potentials based on the electrocatalytic activity of gold nanoparticle-functionalized porphyrinyl COFs nanocomposites toward [Fe(CN)] and the signal probe of MB encapsulated in the aptamer-modified alkynyl COFs.
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