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Single-pixel cameras provide a means to perform imaging at wavelengths where pixelated detector arrays are expensive or limited. The image is reconstructed from measurements of the correlation between the scene and a series of masks. Although there has been much research in the field in recent years, the fact that the signal-to-noise ratio (SNR) scales poorly with increasing resolution has been one of the main limitations prohibiting the uptake of such systems. Microscanning is a technique that provides a final higher resolution image by combining multiple images of a lower resolution. Each of these low resolution images is subject to a sub-pixel sized lateral displacement. In this work we apply a digital microscanning approach to an infrared single-pixel camera. Our approach requires no additional hardware, but is achieved simply by using a modified set of masks. Compared to the conventional Hadamard based single-pixel imaging scheme, our proposed framework improves the SNR of reconstructed images by ∼ 50 % for the same acquisition time. In addition, this strategy also provides access to a stream of low-resolution 'preview' images throughout each high-resolution acquisition.
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http://dx.doi.org/10.1364/OE.24.010476 | DOI Listing |
Phys Eng Sci Med
September 2025
Department of Physics, Faculty of Mathematics and Natural Sciences, Universitas Indonesia, Depok, 16424, Indonesia.
This study introduces a novel optimization framework for cranial three-dimensional rotational angiography (3DRA), combining the development of a brain equivalent in-house phantom with Figure of Merit (FOM) a quantitative evaluation method. The technical contribution involves the development of an in-house phantom constructed using iodine-infused epoxy and lycal resins, validated against clinical Hounsfield Units (HU). A customized head phantom was developed to simulate brain tissue and cranial vasculature for 3DRA optimization.
View Article and Find Full Text PDFMed Phys
September 2025
Department of Radiology, Stony Brook University, New York, USA.
Background: In contrast-enhanced digital mammography (CEDM) and contrast-enhanced digital breast tomosynthesis (CEDBT), low-energy (LE) and high-energy (HE) images are acquired after injection of iodine contrast agent. Weighted subtraction is then applied to generate dual-energy (DE) images, where normal breast tissues are suppressed, leaving iodinated objects enhanced. Currently, clinical systems employ a dual-shot (DS) method, where LE and HE images are acquired with two separate exposures.
View Article and Find Full Text PDFNMR Biomed
October 2025
Biomedical Engineering, University of Michigan, Ann Arbor, Michigan, USA.
Understanding gastric physiology in rodents is critical for advancing preclinical neurogastroenterology research. However, existing techniques are often invasive, terminal, or limited in resolution. This study aims to develop a non-invasive, standardized MRI protocol capable of capturing whole-stomach dynamics in anesthetized rats with high spatiotemporal resolution.
View Article and Find Full Text PDFJ Appl Clin Med Phys
September 2025
Department of Radiation Oncology, Virginia Commonwealth University, Richmond, Virginia, USA.
Purpose: Real‑time magnetic resonance-guided radiation therapy (MRgRT) integrates MRI with a linear accelerator (Linac) for gating and adaptive radiotherapy, which requires robust image‑quality assurance over a large field of view (FOV). Specialized phantoms capable of accommodating this extensive FOV are therefore essential. This study compares the performance of four commercial MRI phantoms on a 0.
View Article and Find Full Text PDFJ Am Soc Mass Spectrom
September 2025
Department of Chemistry, University of Texas at Austin, Austin, Texas 78712, United States.
An ongoing goal of top-down mass spectrometry is to increase the performance for larger proteins. Using higher energy activation methods, like 193 nm ultraviolet photodissociation (UVPD), offers the potential to cause more extensive fragmentation of large proteins and thereby yield greater sequence coverage. Obtaining high sequence coverage requires confident identification and assignment of fragment ions, and this process is hampered by spectral congestion and low signal-to-noise ratio (S/N) of the fragment ions.
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