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We investigated the physical dynamics of San Quintin Bay, a coastal lagoon located on the Pacific coast of northern Baja California, Mexico. We implemented, validated and used a finite element 2-D hydrodynamic model to characterize the spatial and temporal variability of the hydrodynamic of the bay in response to variability in the tidal regime and in meteorological forcing patterns. Our analysis of general circulation, residual currents, residence times, and tidal propagation delays allowed us to characterize spatial variability in the hydrodynamic basin features. The eulerian water residence time is -on average and under reference conditions- approximately 7days, although this can change significantly by region and season and under different tidal and meteorological conditions. Ocean upwelling events that bring colder waters into the bay mouth affect hydrodynamic properties in all areas of the lagoon and may affect ecological dynamics. A return to pre-upwelling conditions would take approximately 10days.
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http://dx.doi.org/10.1016/j.marpolbul.2016.04.030 | DOI Listing |
Med Eng Phys
October 2025
Mechanical Engineering Department KVGIT Jaipur, Rajasthan, India.
Triply periodic minimal surfaces have garnered significant interest in the field of biomaterial scaffolds due to their unique structural properties, including a high surface-to-volume (S/V) ratio, tunable permeability, and the potential for enhanced biocompatibility. Bone scaffolds necessitate specific features to effectively support tissue regeneration. This study examines the permeability and active cell proliferation area of advanced Triply Periodic Minimal Surface (TPMS) lattice structures, focusing on a novel lattice design.
View Article and Find Full Text PDFMed Eng Phys
October 2025
Department of Mechanical Engineering, University of Cape Town, 7701, South Africa; Centre for Research in Computational and Applied Mechanics (CERECAM), University of Cape Town, 7701, South Africa.
The usability and versatility of autoinjectors in managing chronic and autoimmune diseases have made them increasingly attractive in medicine. However, investigations into autoinjector designs require an understanding of the kinematic properties and fluid behaviour during injection. To optimise injection efficiency, this study develops a mathematical and computational fluid dynamics (CFD) model of an IM autoinjector by investigating the effects of viscosity, needle length, needle diameter, and medication volume on the injection process.
View Article and Find Full Text PDFJ Colloid Interface Sci
September 2025
School of Materials, Shenzhen Campus of Sun Yat-sen University, Shenzhen 518107, China. Electronic address:
Harnessing the significant buildup of lactic acid (LA) within the tumor microenvironment (TME) for metabolic manipulation presents a promising avenue for cancer treatment. Nevertheless, single-agent therapies often fail to address the complex and varying needs of TME heterogeneity, posing a substantial scientific hurdle in oncology. In this context, we employ asymmetric mesoporous silica nanoparticles (AMS NPs) as delivery vehicles, simultaneously loading them with zinc‑cobalt‑manganese ferrite nanoparticles (ZCMF NPs), lactate oxidase (LOX), and doxorubicin (DOX).
View Article and Find Full Text PDFProc Natl Acad Sci U S A
September 2025
The Biorobotics Institute, Scuola Superiore Sant'Anna, Pisa 56025, Italy.
Aquatic microorganisms typically inhabit a heterogeneous resource landscape, composed of localized and transient patches. To effectively exploit these resources, they have evolved a wide range of feeding strategies that combine chemotactic motility with active feeding flows. However, there is a notable lack of experimental studies that examine how these active flows shape resource fields to optimize feeding.
View Article and Find Full Text PDFThe Ordos Basin's Hangjinqi Shiligahan west zone Xiashihezi Formation 1 Member gas reservoir exhibits significant exploration and development potential. However, its sedimentation and reservoir characteristics are poorly understood. To address this, geological, seismic, macroscopic, and microscopic methods are combined.
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