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Purpose: To evaluate the initial effects and operative techniques for treating recurrent mediastinal lymph node metastasis using CT-guided nontranspulmonary puncture interstitial implantation of (125)I seeds.
Methods And Materials: Thirteen patients (eight men and five women) with a total of 14 recurrent mediastinal lymph node metastatic lesions underwent CT-guided nontranspulmonary puncture interstitial implantation of (125)I seeds.
Results: We used the transpleural cavity approach for six cases (air injection of 200-600 mL), the transsternal approach for three cases, the supersternal approach for one case, and the parasternal/paraspinal approach for the remaining cases (including two cases using the salinoma window technique). All patients had good operational tolerance. Mean followup was 16.3 months, with 12 complete response lesions and 2 partial response lesions.
Conclusions: Treating recurrent mediastinal lymph node metastasis using CT-guided nontranspulmonary puncture interstitial implantation of (125)I seeds is safe and effective, with minimal trauma, evident local therapeutic effects, and does not damage lung tissue. However, comprehensive application of multiple puncture assistive technologies, and skill, is required due to the important, anatomically complex structures in the mediastinum.
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http://dx.doi.org/10.1016/j.brachy.2016.02.007 | DOI Listing |
Cureus
August 2025
School of Medicine, University of Costa Rica, San José, CRI.
Hibernomas are infrequent brown adipose tissue tumors that can mimic various other soft tissue tumors, both malignant and benign, and multiple imaging modalities are usually used in the diagnostic approach. We present the case of a 30-year-old female patient who was initially diagnosed with a mediastinal hibernoma through complete excisional biopsy in 2022 and underwent surgical resection at that time. She required a second surgical intervention in 2024 due to recurrence and is now being evaluated for a second recurrence using fluorine-18 fluorodeoxyglucose positron-emission tomography/computed tomography (18F-FDG PET/CT), reporting an extensive polylobulated mediastinal tumor intercalating normometabolic and discretely hypermetabolic zones.
View Article and Find Full Text PDFFront Med (Lausanne)
August 2025
Department of Thyroid Breast Surgery, The Affiliated Yixing Hospital of Jiangsu University, Wuxi, China.
Human Immunodeficiency Virus (HIV)-induced immunosuppression represents a potential risk factor for tumorigenesis and cancer progression, though existing studies have not conclusively established the association between HIV infection and the proliferation/metastasis of papillary thyroid carcinoma (PTC). We present a rare case of a 26-year-old male patient who exhibited rapid cervical tumor enlargement with extensive high-burden lymphatic metastasis following HIV infection. Imaging examinations revealed a cystic-solid thyroid mass with multiple lymphadenopathies in bilateral cervical regions, mediastinum, and axillae.
View Article and Find Full Text PDFEur J Surg Oncol
September 2025
Division of Thoracic Surgery, University and Hospital Trust, Ospedale Borgo Trento, Verona, Italy. Electronic address:
Background: Despite significant advancements in early detection and treatment, cancer recurrence remains a major challenge, affecting 30-55 % of patients within two years following surgery. Tumor recurrence is commonly classified as local, locoregional, regional or distant, yet a unified consensus on these definitions is still lacking.
Materials And Methods: A systematic review of the recent literature (2020-2024) was conducted in accordance with PRISMA guidelines to collect site-specific recurrence definitions.
Exp Ther Med
October 2025
Department of Blood Transfusion Medicine, Taihe Hospital, Hubei University of Medicine, Shiyan, Hubei 442000, P.R. China.
Pulmonary epithelial-myoepithelial carcinoma (P-EMC) is a rare type of salivary gland tumour of the lung. Due to its rarity and lack of long-term follow-up data, there is no established standard for optimal treatment or duration of follow-up. The present study reports the case of a 58-year-old female patient with P-EMC originating from the middle part of the bronchus and presenting as an endobronchial mass in the left superior lobe.
View Article and Find Full Text PDFCase Rep Infect Dis
August 2025
Clinical Tuberculosis and Epidemiology Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran.
was first identified in a patient with HIV. Here, we describe a 40-year-old man with prolonged fever and mediastinal and abdominal lymphadenopathy, who was initially misdiagnosed with sarcoidosis. A molecular study was conducted after mycobacterium was isolated from a lymph node biopsy, leading to the identification of .
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