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Vet World
June 2025
Department of Microbiology, Faculty of Veterinary Science, Chulalongkorn University, Bangkok 10330, Thailand.
Background And Aim: Industrial-scale probiotic production requires economically viable media formulations that do not compromise strain functionality. This study aimed to develop a cost-effective medium for cultivating 22F (L22F), a probiotic candidate isolated from swine feces, while evaluating its industrial viability and functional metabolic profile.
Materials And Methods: Carbon (glucose, sucrose, and dextrose) and nitrogen (yeast extract, soy protein isolate, and whey protein concentrate) sources were screened using one-variable-at-a-time and Plackett-Burman design, followed by Response Surface Methodology for optimization.
Food Funct
July 2025
Department of Agricultural, Food, Environmental and Animal Science, University of Udine, Italy.
The gut microbiome plays a key role in modulating human health and well-being. Exopolysaccharides (EPS) produced by lactic acid bacteria (LAB) are emerging as novel polymers that could exert a prebiotic effect modification of this microbiome. Thus, incorporation of EPS to enhance food functionality is of interest.
View Article and Find Full Text PDFBiomed Eng Online
July 2025
Women Healthcare Department, Hangzhou Women's Hospital (Hangzhou Maternity and Child Health Care Hospital), Hangzhou, 310008, China.
Perimenopause marks a critical transition in women's lives, characterized by declining estrogen levels that trigger profound physiological and psychological changes, impacting quality of life and increasing susceptibility to age-related degenerative diseases. This review systematically examines the intricate relationships among menopause, disease associations, microbiome alterations, and intervention strategies. Estrogen fluctuations disrupt the microbial balance in the vagina, intestine, urethra, and oral cavity, contributing to microecological imbalance and heightened disease risk.
View Article and Find Full Text PDFMenopause
July 2025
Department of Obstetrics and Gynecology, State University of Campinas (UNICAMP- Universidade Estadual de Campinas), Campinas, São Paulo, Brazil.
Objectives: To correlate the urinary excretion of equol with intestinal microbiota in response to isoflavone supplementation alone or in combination with probiotics, and to compare these results with those of hormone therapy in postmenopausal women.
Methods: A pilot study was conducted on 47 postmenopausal women aged 40-60 years. Participants were randomly assigned to one of three groups: (A) oral isoflavone (150 mg dry extract of Glycine max); (B) isoflavone plus probiotic (Lactobacillus acidophilus, Lactobacillus casei, Lactococcus lactis, Bifidobacterium bifidum, and Bifidobacterium lactis); or (C) hormone therapy (1 mg estradiol/0.
J Dairy Sci
September 2025
Key Laboratory of Dairy Biotechnology and Engineering, Ministry of Education, Inner Mongolia Agricultural University, Hohhot, 010018, China; Key Laboratory of Dairy Products Processing, Ministry of Agriculture and Rural Affairs, Inner Mongolia Agricultural University, Hohhot, 010018, China; Inner Mo
Bifidobacteria, a significant component of human gut microbiota, play a crucial role in maintaining human health. Studies have shown that the composition of gut microbiome is closely related to the geographical environment, ethnicity, and dietary structure of the host. Currently, most of the mainstream probiotics on the market are based on the gut microbiota characteristics of Western populations, which may not be completely suitable for the gut environment of Chinese people.
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