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http://dx.doi.org/10.1016/j.joms.2015.10.032 | DOI Listing |
Orthod Craniofac Res
September 2025
Department of Orthodontics, College of Dentistry, University of Florida, Gainesville, Florida, USA.
Objective(s): In this pilot study, exosomes from saliva were isolated and tested for the presence of metabolomic biomarkers for physiological external root resorption and/or pathological alveolar bone resorption.
Settings And Sample Population: Saliva samples of 20 individuals in the mixed dentition stage of dental development.
Materials And Methods: Saliva was obtained from healthy control children with resorbing primary teeth or children with localised aggressive periodontitis (LAP) showing alveolar bone loss but little root resorption.
Background And Aims: Whereas the value of endoscopic retrograde cholangiopancreatography (ERCP) training in clinical practice is well known, the impact on stress markers and performance in a virtual reality (VR) simulator is not. The primary aim of the study was to see how the number of clinical ERCPs performed during a 1-year period influenced VR-ERCP performance. A secondary aim was to compare differences in salivary stress marker levels, between the first and final simulator attempts.
View Article and Find Full Text PDFCell Mol Biol (Noisy-le-grand)
September 2025
Department of Dentistry, Al-Esraa University, Baghdad, Iraq.
Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by persistent inflammation and is often associated with poor oral health. Cytokines play a central role in RA immunopathogenesis. This case-control study investigated the involvement of salivary interleukin-17A (IL-17A) and interleukin-18 (IL-18) in RA patients in relation to oral health status.
View Article and Find Full Text PDFClin Oral Investig
September 2025
Department of Periodontics, Saveetha Dental College, Saveetha Institute of Medical and Technology Sciences, SIMATS, Saveetha University, Chennai, Tamil Nadu, India.
Objectives: This study aims to assess periodontal and biochemical parameters and evaluate the salivary Protectin D1 levels in periodontitis patients with and without metabolic syndrome after non-surgical periodontal therapy.
Materials And Methods: Forty patients were categorized into two groups: 20 patients in Group P (systemically healthy patients with stage II/III grade B periodontitis) and 20 patients in Group P+MS (patients with stage II/III grade B periodontitis and metabolic syndrome). Parameters including age, gender, height, weight, body mass index, waist circumference, socio-economic status, oral hygiene index (OHI), modified gingival index (MGI), probing pocket depth, clinical attachment levels, fasting blood glucose, HDL-c, total triglycerides, and blood pressure were recorded.
Spectrochim Acta A Mol Biomol Spectrosc
August 2025
Department of Combination of Mongolian Medicine and Western Medicine Stomatology, Affiliated Hospital of Inner Mongolia Minzu University, Tongliao 028043, China. Electronic address:
To achieve non-invasive early diagnosis and severity monitoring of periodontal disease, this study employed silver nanoparticles as a surface-enhanced Raman Scattering (SERS) substrate for the detection and analysis of salivary SERS spectra from a control group (periodontal health group) and groups with periodontal disease of varying severities (including gingivitis, as well as mild, moderate, and severe periodontitis). The results demonstrated significant differences in salivary SERS spectra between the control group and the gingivitis group, between the control group and the mild periodontitis group, and between the control group and groups with periodontal disease of different severities. Subsequently, based on the dual screening criteria of Variable Importance in Projection (VIP) ≥ 1 and P < 0.
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