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Air pollution health studies of fine particulate matter (diameter ≤2.5 μm, PM2.5) often use outdoor concentrations as exposure surrogates. Failure to account for variability of indoor infiltration of ambient PM2.5 and time indoors can induce exposure errors. We developed and evaluated an exposure model for individuals (EMI), which predicts five tiers of individual-level exposure metrics for ambient PM2.5 using outdoor concentrations, questionnaires, weather, and time-location information. We linked a mechanistic air exchange rate (AER) model to a mass-balance PM2.5 infiltration model to predict residential AER (Tier 1), infiltration factors (Tier 2), indoor concentrations (Tier 3), personal exposure factors (Tier 4), and personal exposures (Tier 5) for ambient PM2.5. Using cross-validation, individual predictions were compared to 591 daily measurements from 31 homes (Tiers 1-3) and participants (Tiers 4-5) in central North Carolina. Median absolute differences were 39% (0.17 h(-1)) for Tier 1, 18% (0.10) for Tier 2, 20% (2.0 μg/m(3)) for Tier 3, 18% (0.10) for Tier 4, and 20% (1.8 μg/m(3)) for Tier 5. The capability of EMI could help reduce the uncertainty of ambient PM2.5 exposure metrics used in health studies.
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http://dx.doi.org/10.1021/acs.est.5b02765 | DOI Listing |
Front Public Health
July 2025
Gastroenterology Department, Chongqing University Fuling Hospital, Chongqing University, Chongqing, China.
Objective: Joint exposure to fine particulate matter (PM₂․₅) and prolonged sedentary behavior in later life may erode physiological reserve and hasten carcinogenesis, yet evidence quantifying their combined impact on incident lung cancer among older Chinese adults is sparse. We investigated whether co-occurrence of high ambient PM₂․₅ and extensive sitting time accelerates incident lung cancer in a nationally representative cohort.
Methods: We analyzed 10,532 adults aged ≥45 years in the China Health and Retirement Longitudinal Study (2011-2018).
Environ Res
July 2024
Department of Environmental Medicine and Climate Science, Icahn School of Medicine at Mt. Sinai, New York, NY, USA; Institute for Climate Change, Environmental Health, and Exposomics, Icahn School of Medicine at Mt. Sinai, New York, NY, USA.
Environ Res
November 2022
School of Public Health, Guangzhou Medical University, Guangzhou, 511436, China. Electronic address:
Previous studies have attempted to clarify the relationship between the occurrence of pulmonary tuberculosis (PTB) and exposure to air pollutants. However, evidence from multi-centres, particularly at the national level, is scarce, and no study has examined the modifying effect of greenness on air pollution-TB associations. In this study, we examined the association between long-term exposure to ambient air pollutants (PM p.
View Article and Find Full Text PDFEnviron Int
February 2022
Division of Sports Science & Physical Education, Tsinghua University, Beijing 100084, China. Electronic address:
Environ Res
September 2019
Swiss Tropical and Public Health Institute, Basel, Switzerland; University of Basel, Basel, Switzerland.
Ambient air pollution represents one of the biggest environmental risks to health. In this study, we estimated the avoidable mortality burden attributable to ambient air pollution in Tehran, and derived the economic impact associated with these health effects. Using PM data from ground-level air pollution measurements in Tehran, we estimated PM exposure for 349 neighborhoods in Tehran, by the Environmental Benefits Mapping and Analysis Program (BenMAP-CE).
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