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Although the finite-difference time-domain (FDTD) technique has been prevailingly used to calculate the electric field intensity (EFI) enhancement at nodular defects in high-reflection (HR) coatings, the physical insight as to how the nodular features contribute to the intensified EFI is not explicitly revealed yet, which in turn limits the solutions that improve the laser-induced damage threshold (LIDT) of nodules by decreasing the EFI enhancement. Here, a simplified model is proposed to describe the intensified EFI in nodules: 1) the nodule works as a microlens and its focal length can be predicted using a simple formula, 2) the portion of incident light that penetrates through the HR coating can be estimated by knowing the angular dependent transmittance (ADT) of the nodule, 3) strong EFI enhancement is created when the focal point is within the nodule and simultaneously a certain portion of light penetrates to the focal position. In the light of the proposed model, a broadband HR coating was used to reduce the EFI enhancement at the seed by a factor about 10, which leads to a 20 times increment of the LIDT. This work therefore not only deepens the physical understanding of EFI enhancement at nodules but also provides a new way to increase the LIDT of multilayer reflective optics.
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http://dx.doi.org/10.1364/OE.23.008609 | DOI Listing |
FEBS J
August 2025
School of Biomolecular Science and Engineering, Vidyasirimedhi Institute of Science and Technology (VISTEC), Rayong, Thailand.
Aldehyde deformylating oxygenase (ADO) plays a crucial role in hydrocarbon biosynthesis by converting C fatty aldehydes into C alkanes, key components of biofuels. However, ADO's low catalytic efficiency and thermostability hinder its industrial application. In this study, we identified a novel ADO from Pseudomonas plecoglossicida (PsADO) using the Enzyme Function Initiative-Enzyme Similarity Tool (EFI-EST).
View Article and Find Full Text PDFSensors (Basel)
August 2025
College of Automation Engineering, Nanjing University of Aeronautics and Astronautics, Nanjing 211106, China.
The junction temperature () is a key parameter reflecting the thermal behavior of Silicon carbide (SiC) MOSFETs and is essential for condition monitoring and reliability assessment in power electronic systems. However, the limited temperature sensitivity of switching characteristics makes it difficult for traditional single temperature-sensitive electrical parameters (TSEPs) to achieve accurate estimation. To address this challenge and enable practical thermal sensing applications, this study proposes an accurate, application-oriented estimation method based on multivariate linear regression (MLR) using turn-off current fall time () and fall loss () as complementary TSEPs.
View Article and Find Full Text PDFJ Orthop Surg Res
July 2025
Department of Trauma and Microreconstructive Surgery, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, 830054, Xinjiang, China.
Background: This analysis aimed to assess the functional outcomes of patients with post-traumatic distal humerus defects and nonunions treated by bone transportation combined with internal fixation, containing two surgical techniques designed to enhance docking site union and functional recovery in critical distal humerus defects.
Methods: This retrospective study included 16 patients with post-traumatic distal humerus defects who underwent bone transportation combined with internal fixation between June 2017 and December 2023. Clinical records and consecutive X-ray images were reviewed to assess bone regeneration and alignment.
J Inflamm Res
June 2025
Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang, West Java, 45363, Indonesia.
Introduction: Diabetic wounds present a significant challenge due to delayed healing and susceptibility to infection. Conventional therapies often fall short of achieving complete and timely wound repair. This study investigates the potential of α-mangostin (αM) and its propolis-based nanostructured lipid carrier (NLC-P-αM) formulation as novel therapeutic agents for diabetic wound healing.
View Article and Find Full Text PDFInt J Health Econ Manag
April 2025
Directorate of Analytical, Economic and Actuarial Studies in Health, Instituto de Evaluación Tecnológica en Salud (IETS), Bogotá, D.C., Colombia.
Expanding explicit Health Benefit Plans (HBP) is a key strategy for achieving universal health coverage while maintaining financial sustainability. However, little is known about the broader effects of periodic updates to these plans on healthcare utilization, expenditures, and market dynamics. This study examines the impact of including new health technologies in Colombia's HBP covered by the Capitation Payment Unit (CPU) between 2012 and 2019, using administrative data and a difference-in-differences approach with multiple periods.
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