Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Objective: Vacuum assisted closure is a reported technique to manage complex wounds. We have utilized this technique by using simple locally available material in the management of our patients on outpatient basis. The objective of this study is to present our experience.
Methods: This study was conducted from June 2011 to June 2013 at Dow University Hospital and Aga Khan University Hospital, Karachi. There were 38 patients managed with vacuum assisted closure. Mean age was 56±7.8 years. Twenty three patients presented with necrotizing fasciitis and 15 patients with gangrene. Lower limbs were involved in majority of the patients. Debridement or amputations were done. Vacuum dressing was changed twice weekly in outpatient department. Wounds were closed secondarily if possible or covered with split thickness skin graft in another admission.
Results: All the wounds were successfully granulated at the end of vacuum therapy. Mean hospital stay was 7.5 days. Vacuum dressing was applied for a mean of 20 days. There was reduction in the size of the wound. Thirteen patients underwent secondary closure of the wound under local anesthesia, 18 patients required coverage with split thickness skin graft and 7 patients healed with secondary intention.
Conclusion: Vacuum assisted closure appeared to be an effective method to manage complex diabetic wounds requiring sterile wound environment.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4386165 | PMC |
| http://dx.doi.org/10.12669/pjms.311.6093 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Single-Cell Membrane Molecular Cartography Enabled by Nanoengineered VUV-LDI Mass Spectrometry Imaging.
Anal Chem
September 2025
State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, China.
Deciphering the multicomponent of cell membranes at the single-cell level is critical for understanding pathological mechanisms such as tumor metastasis, yet remains technically daunting due to the membrane's nanoscale thickness and ultralow molecular abundance. Here, we introduce a surface-assisted vacuum ultraviolet laser desorption-ionization mass spectrometry imaging (SAVUVDI-MSI) platform that overcomes long-standing challenges of cytoplasmic interference and insufficient sensitivity. Leveraging the nanoscale depth profiling capability of VUV-LDI, we achieve precise ablation of a single-cell membrane.
View Article and Find Full Text PDFOptimizing Availability and Appropriate Use of Assisted Vaginal Birth: Protocol for Generic Formative Research of an Implementation Preparation.
JMIR Res Protoc
September 2025
Gender and Women's Health Unit, Nossal Institute for Global Health, School of Population and Global Health, The University of Melbourne, Carlton, Australia.
Background: Assisted vaginal birth is a lifesaving procedure where health workers use special devices to expedite birth vaginally when some complications emerge, such as due to prolonged labor. When the use of assisted vaginal birth is possible and appropriate, it provides benefits over cesarean section. These benefits include shorter recovery, reduced hospital stays, lower risks of complications, cost savings, and greater likelihood of vaginal birth in future pregnancies.
View Article and Find Full Text PDFFinite element and preclinical analysis of tissue response to negative pressure wound therapy with a felted foam containing 10 mm through holes.
Front Bioeng Biotechnol
August 2025
Solventum, St. Paul, MN, United States.
Introduction: Not all wound patients are candidates for surgical debridement. A felted, reticulated open cell foam with an array of 10 mm holes (VFCC) for use with instillation therapy has been used to eliminate non-viable tissue from patient wound beds. The mechanisms for this have not been fully elucidated.
View Article and Find Full Text PDFDiscarded sericultural mulberry branch based triple layer composite phase change material with lignin enhanced thermal management capability.
Int J Biol Macromol
September 2025
Key Laboratory of Bio-Based Material Science and Technology of Ministry of Education, Northeast Forestry University, Harbin, 150040, China. Electronic address:
With the exhaustion of fossil fuels, prior phase change materials are characterized by such drawbacks as poor thermal conductivity, weak shape stability, and high costs. Therefore, the preparation of phase change materials with brilliant thermal-insulating properties, high thermal conductivity, and leakage-free properties has emerged as a crucial research focus. Herein, a sericultural mulberry branch-derived (SMB) composite phase change material was prepared by deep eutectic solvent pretreated SMB and vacuum-assisted impregnated paraffin wax with cupric oxide (CuO).
View Article and Find Full Text PDFDevelopment and performance optimization of a portable Gas Chromatography - Photoionization Detection system for trace electrolyte leakage detection in lithium batteries.
J Chromatogr A
August 2025
School of Mechanical and Electrical Engineering, Schoow University, Suzhou 215131, China. Electronic address:
With the widespread application of lithium batteries in energy storage systems, their safety concerns have attracted increasing attention. Electrolyte leakage, as one of the primary safety hazards, necessitates highly sensitive and rapid detection technologies for early warning. Addressing the limitations of conventional methods (e.
View Article and Find Full Text PDF