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Patients who underwent hepatic resection of locally recurrent tumors after radiofrequency ablation(RFA)for colorectal liver metastases (CRLM) were retrospectively investigated. Among 12 patients who underwent RFA as first-line treatment for CRLM, 7 experienced local recurrence, 5 of whom (6 nodules) underwent hepatic resection. The mean diameter (range) of the tumors was 9.5(5-16) mm, and they were located at S2, S7 (adjacent to the right hepatic vein), S5/6 (between the root of the anterior and the posterior Glisson's pedicle), S1r (right paracaval portion), S6, and S3. No local recurrence was observed after hepatic resection. In conclusion, hepatic resection must be the initial therapeutic strategy for CRLM, and the indication for RFA must be considered carefully.
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Ann Surg Oncol
September 2025
Department of Gastroenterological and Transplant Surgery, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
Background: Hepatocellular carcinoma (HCC) frequently invades the portal vein, leading to early recurrence and a poor prognosis. However, the mechanisms underlying this invasion remain unclear. In this study, we aimed to detect portal vein circulating tumor cells (CTCs) using a Glypican-3-positive detection method and evaluate their prognostic significance.
View Article and Find Full Text PDFKhirurgiia (Mosk)
September 2025
Dagestan State Medical University, Makhachkala, Russia.
Objective: To analyze the effectiveness of minimally invasive surgery for small and medium sized liver cysts.
Material And Methods: We used minimally invasive technologies in 331 patients with echinococcal liver cysts (small cysts (<3.5 cm) - 49 (14.
Int J Surg
September 2025
Department of Interventional Radiology, Hainan Hospital of the General Hospital of the People's Liberation Army of China, Sanya, China.
Background: Since 2013, we have performed conversion surgery after hepatic arterial infusion chemotherapy (HAIC) for initially unresectable locally advanced hepatocellular carcinoma (LA-HCC).
Methods: Between 2013 and 2021, we assessed the surgical and oncological outcomes and pathological findings of patients with LA-HCC without extrahepatic spread (EHS) whose tumors converted from unresectable to resectable status with the New-FP regimen HAIC.
Results: We censored 153 patients with LA-HCC (Child-Pugh A, without EHS) indicated for HAIC.
World J Surg
September 2025
Department of Hepatobiliary-Pancreatic Surgery, Juntendo University School of Medicine, Tokyo, Japan.
Background: Achieving R0 resection in hepatopancreatobiliary (HBP) surgery frequently necessitates venous resection and reconstruction. Autologous grafts offer a promising solution, particularly in complex resections where infection risk or graft availability limit the use of synthetic or donor grafts. However, clinical data on the outcomes of autologous venous grafts remain limited.
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