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Purpose: Differentiated thyroid cancer has a good prognosis and high incidence in young women. Since endoscopic techniques were first recorded in 1996, surgical indications of endoscopic thyroidectomy have broadened. Therefore, the aim of this study is to investigate the usefulness of endoscopic thyroidectomy in clinically lymph node negative (cN0) thyroid cancer patients, based on oncologic completeness and safety, considering cosmetic outcomes.
Methods: From July 2009 to June 2011, a total of 166 cases had undergone endoscopic thyroidectomy using the BABA (bilateral axillo-breast approach) method or conventional open thyroidectomy by one surgeon. Finally, excluding 72 patients, 94 patients with cN0 thyroid cancer were divided into two groups according to operative methods and analyzed to compare differences between the two methods retrospectively (endoscopic group, n = 49; conventional open group, n = 45).
Results: We practiced comparative analysis for clinicopathologic characteristics, surgical outcomes including postoperative complications, and recurred cases during follow-up periods of each group. The results showed there was a tendency for patients, young, women rather than men, and having small size of thyroid cancer, to prefer endoscopic surgery to open surgery. Meanwhile, in postoperative complications, there were no statistically significant differences. During short follow-up periods, no recurrence or mortality case was observed.
Conclusion: Endoscopic thyroidectomy is a feasible and safe method for the treatment of clinically lymph node negative (cN0) thyroid cancer.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4325647 | PMC |
http://dx.doi.org/10.4174/astr.2015.88.2.69 | DOI Listing |
J Natl Compr Canc Netw
September 2025
aMedStar Georgetown University Hospital, Washington, DC.
J Natl Compr Canc Netw
September 2025
aDepartment of Head and Neck Surgery, Fudan University Shanghai Cancer Center, Shanghai, China.
Pol Merkur Lekarski
September 2025
BUKOVINIAN STATE MEDICAL UNIVERSITY, CHERNIVTSI, UKRAINE.
Objective: Aim: To find out new objective criteria for laser histological differential diagnosis of thyroid pathology based on the use of a digital method of layer-by-layer polarization-interference mapping of polarization ellipticity maps of microscopic images of native histological sections of thyroid biopsy.
Patients And Methods: Materials and Methods: Four groups of patients were studied: control group 1 - healthy donors (51 patients); study group 2 - patients with nodular goiter (51 patients); study group 3 - patients with autoimmune thyroiditis (51 patients); study group 4 - patients with papillary cancer (51 patients). Methods used: polarization-interference, statistical.
Inflamm Res
September 2025
Department of General Surgery, Beijing Anzhen Hospital, Capital Medical University, No.2 Anzhen Road, Chaoyang District, Beijing, 100029, China.
Background: The roles of long non-coding RNAs (lncRNAs) in the progression of various human tumors have been extensively studied. However, their specific mechanisms and therapeutic potential in Triple-Negative Breast Cancer (TNBC) remain to be fully elucidated.
Materials And Methods: The qRT-PCR assay was utilized to assess the relative mRNA levels of TFAP2A-AS1, PHGDH, and miR-6892.
Ann Med
December 2025
Department of Thyroid Oncology, Chongqing Key Laboratory of Translational Research for Cancer Metastasis and Individualized Treatment, Chongqing University Cancer Hospital, Chongqing, P.R. China.