98%
921
2 minutes
20
Background: Home mechanical ventilation (HMV) is a routine method of treatment for patients with chronic ventilatory failure. Over the last 20 y, a marked development in HMV has been noted in terms of its prevalence and the changing proportion of patients with various indications. However, data on HMV come exclusively from the developed countries of Europe and North America. Nowadays, we can see the emergence of HMV in less developed countries. This study aimed to describe the development of HMV in Poland.
Methods: Data from the largest HMV centers were retrospectively evaluated with regard to cause of respiratory failure, ventilation technique, and characteristics of the HMV-implementing institution.
Results: The number of subjects treated with HMV increased from 8 in 2000 to 928 in 2010. Neuromuscular diseases remained the main indication. However, their relative contribution decreased from 100 to 51% in favor of pulmonary diseases (an increase from 0 to 21%) and hypoventilation syndromes (0% in 2000 and 11% in 2010). The majority of the HMV population treated between 2000 between 2008 was ventilated by tracheostomy; however, since 2007, the percentage of subjects on noninvasive ventilation significantly increased and was equal to the number of tracheostomized subjects. HMV was initiated mainly in ICUs. However, their role systematically diminished, and an increasing number of subjects were recruited in respiratory departments.
Conclusions: The prescription pattern of HMV in Poland has evolved, and there is a clear shift from neuromuscular to respiratory diseases. The prevalence of ventilation via tracheostomy still remains very high in comparison with other European countries. The Polish experience could be useful for countries with emerging HMV care systems.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.4187/respcare.03126 | DOI Listing |
Front Cell Infect Microbiol
September 2025
State Key Laboratory of Vaccines for Infectious Diseases, Xiang-An Biomedicine Laboratory, National Innovation Platform for Industry-Education Integration in Vaccine Research, Department of Laboratory Medicine, School of Public Health, Xiamen University, Xiamen, China.
infections represent a significant public health concern. Despite their clinical relevance, the genetic determinants underlying bacterial fitness and virulence remain incompletely characterized. In this study, we systematically identified genes involved in host adaptation by generating a transposon mutant library and integrating a infection model with transposon sequencing (Tn-seq) technology.
View Article and Find Full Text PDFMol Psychiatry
September 2025
Graduate Program in Biological Sciences: Biochemistry, Universidade Federal do Rio Grande do Sul (UFRGS), Rua Ramiro Barcelos 2500, 90035-003, Porto Alegre, Rio Grande do Sul, Brazil.
Background: Fluorodeoxyglucose (FDG)-PET hypometabolism is considered a biomarker of neurodegeneration. However, recent evidence revealed that glial cells contribute to the FDG-PET signal. In this context, microglial changes have been evaluated with 18-kDa translocator protein (TSPO)-PET radiopharmaceuticals.
View Article and Find Full Text PDFCureus
July 2025
Department of Prosthodontics, Sibar Institute of Dental Sciences, Guntur, IND.
Introduction: This in vitro study aimed to evaluate the effects of three chemical disinfectants, glutaraldehyde, sodium hypochlorite, and chlorhexidine gluconate, on the surface microhardness of acrylic resin denture teeth. The objectives of this study were to assess and compare the impact of these disinfectants on microhardness following repeated disinfection cycles.
Materials And Methods: This in vitro study was conducted at the Department of Prosthodontics, involving 76 acrylic resin denture teeth (Premadent, Premadent Dental Products, Delhi, India) embedded in self-cure acrylic resin (DPI-RR Cold Cure, Dental Products of India, Mumbai, India) using a vinyl polysiloxane putty mold (Elite HD+ Putty, Zhermack SpA, Badia Polesine, Italy).
Scand J Caring Sci
September 2025
Department of Intensive Care, Aarhus University Hospital, Aarhus N, Denmark.
Background: Working as a personal care assistant (PCA) in the homes of mechanical ventilation users can be challenging due to the job's complexity. Research indicates that a poor work environment among PCAs could lead to risks of resignations and a high staff turnover, potentially affecting healthcare quality in home mechanical ventilation (HMV) setups.
Aim: To explore work-life perceptions of Danish PCAs working in HMV settings, with a specific focus on communication quality, physical and psychological work environment and the PCA training programme.
Lakartidningen
August 2025
doktorand, bitr överläkare, Smärtrehabilitering, Skånes universitetssjukhus Lund.
There is a lack of evidence for long-term opioid treatment of chronic non-cancer pain. According to European guidelines, opioids should not be used for primary chronic pains. It is important to continuously assess the benefits and harms of each opioid treatment and, if indicated, discontinue it as early as possible to prevent an adverse trajectory.
View Article and Find Full Text PDF