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Integrated global power from the primary structures that composed the Default Mode Network (DMN) and from a random collection of other structures were measured by sLORETA (standardized low-resolution electromagnetic tomography) for young university volunteers who had completed an inventory that contained a subscale by which egocentricity has been inferred. Subjects who exhibited higher scores for egocentricity displayed significantly more power within the DMN structures relative to comparison areas. This was not observed for individuals whose egocentricity scores were lowest where the power differences between the DMN and comparison structures were not significant statistically. DMN power was greater in the right hemisphere than the left for men but greater in the left hemisphere than the right for women. The results are consistent with our operating metaphor that elevation of power or activity within the DMN is associated with greater affiliation with the self and its cognitive contents.
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http://dx.doi.org/10.2174/1874440001408010005 | DOI Listing |
J Pain Res
September 2025
Radiology Department, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, People's Republic of China.
Purpose: Previous studies have revealed alterations of the functional connectivity of the brain networks in ankylosing spondylitis (AS). Fractional amplitude of low-frequency fluctuations (fALFF) and regional homogeneity (ReHo) are both voxel-based functional metrics capable of estimating local spontaneous neural activities. This study aimed to investigate the local spontaneous neural activities in AS patients by utilizing the analytical approaches of fALFF and ReHo.
View Article and Find Full Text PDFJAACAP Open
September 2025
Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Objective: Despite rapid advancements in understanding of cognitive disengagement syndrome (CDS) in children, less is known about the neural correlates of CDS. The aim of this study was to examine associations between CDS symptom severity and connectivity within and between specific brain networks.
Method: The study recruited 65 right-handed children (ages 8-13 years; 36 boys) with the full continuum of CDS symptom severity from the community.
JAACAP Open
September 2025
University of Calgary, Calgary, Alberta, Canada.
Objective: Psychological distress (eg, anxiety and depression) during pregnancy can disrupt fetal brain development and negatively affect infant behavior. Prenatal distress rose substantially during the COVID-19 pandemic according to most, but not all, studies, raising concerns about its potential effects on brain connectivity and behavior in infants.
Method: We investigated 63 mother-infant pairs as part of the Pregnancy during the COVID-19 Pandemic study.
Mol Psychiatry
September 2025
Research Group Cognition and Plasticity, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany.
Background: Peripartum depression (PPD) is a form of major depressive disorder (MDD) that begins during the peripartum period and poses a significant mental health challenge affecting 10 to 29% of women.
Objective: This systematic review and multimodal activation likelihood estimation (ALE) meta-analysis explored the distinct structural, functional, and metabolic features of the PPD brain as compared to female non-peripartum MDD.
Methods: For this purpose, we conducted a comprehensive literature search in PubMed, Embase and PsycINFO databases to identify peer-reviewed original studies investigating the neural correlates associated with PPD or fMDD.
Neuropsychopharmacology
September 2025
Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.
Severe worry is a transdiagnostic, highly prevalent symptom, difficult to treat and associated with significant morbidity in late life. Understanding the neural correlates of worry induction and reappraisal in older adults is key to developing novel treatments. We recruited 124 older adults ( ≥ 50 years old) with varying worry severity and clinical comorbidity (27% generalized anxiety disorder, 23% depressive disorders).
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