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Introduction: Substance abuse interventions tailored to the individual level have produced effective outcomes for a wide variety of behaviors. One approach to enhancing tailoring involves using cluster analysis to identify prevention subtypes that represent different attitudes about substance use. This study applied this approach to better understand tailored interventions for smoking and alcohol prevention.
Methods: Analyses were performed on a sample of sixth graders from 20 New England middle schools involved in a 36-month tailored intervention study. Most adolescents reported being in the Acquisition Precontemplation (aPC) stage at baseline: not smoking or not drinking and not planning to start in the next six months. For smoking (N=4059) and alcohol (N=3973), each sample was randomly split into five subsamples. Cluster analysis was performed within each subsample based on three variables: Pros and Cons (from Decisional Balance Scales), and Situational Temptations.
Results: Across all subsamples for both smoking and alcohol, the following four clusters were identified: (1) Most Protected (MP; low Pros, high Cons, low Temptations); (2) Ambivalent (AM; high Pros, average Cons and Temptations); (3) Risk Denial (RD; average Pros, low Cons, average Temptations); and (4) High Risk (HR; high Pros, low Cons, and very high Temptations).
Conclusions: Finding the same four clusters within aPC for both smoking and alcohol, replicating the results across the five subsamples, and demonstrating hypothesized relations among the clusters with additional external validity analyses provide strong evidence of the robustness of these results. These clusters demonstrate evidence of validity and can provide a basis for tailoring interventions.
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http://dx.doi.org/10.1016/j.addbeh.2014.09.001 | DOI Listing |
Kardiologiia
September 2025
Research Institute of Therapy and Preventive Medicine, Branch of the Federal Research Center Institute of Cytology and Genetics of the Siberian Branch of the Russian Academy of Sciences, Novosibirsk.
Aim To identify non-pharmacological factors associated with ineffective blood pressure (BP) control among individuals with arterial hypertension (AH) in a Siberian urban population sample.Material and methods A considerable proportion of individuals with AH does not achieve BP goals. BP control is influenced by a number of non-drug determinants, including non-modifiable and multiple modifiable factors.
View Article and Find Full Text PDFFront Psychiatry
August 2025
Department of Neurosurgery, Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Introduction: Anxiety, depression, and insomnia are common among older patients with tuberculosis (TB), yet their associations with inflammatory responses and drug-induced liver injury (DILI) remain insufficiently explored. This study aimed to identify distinct inflammation-DILI phenotypes in older TB patients and examine differences in anxiety, depression, and insomnia across subgroups.
Methods: In this cross-sectional study, 251 older TB patients were evaluated.
Nutr Metab Cardiovasc Dis
July 2025
Department of Pharmacy, Women and Children's Hospital, School of Medicine, Xiamen University, 10# Zhenhai Road, Xiamen, China. Electronic address:
Background And Aims: Adolescent hypertension is a growing public health concern, with oxidative stress emerging as a pivotal factor in its development. Oxidative Balance Score (OBS) consists of 20 components, including 16 nutrients (such as carotenoids, riboflavin, copper, etc.) and 4 lifestyle factors (physical activity, BMI, alcohol consumption, and smoking), with higher scores indicating increased exposure to antioxidants.
View Article and Find Full Text PDFClin Gastroenterol Hepatol
September 2025
Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University; State Key Laboratory of Digestive Health; National Clinical Research Center for Digestive Disease; Beijing Key Laboratory of Early Gastrointestinal Cancer Medicine and Medical Devices. Electronic address: shansh
Background & Aims: To investigate association between socioeconomic status (SES) and risk of incident irritable bowel syndrome (IBS), and mediating role of lifestyle factors.
Methods: Participants free of IBS at recruitment were included in this retrospective analysis of a prospectively collected cohort (N=353,790). SES was assessed through household income, education and employment status, with different patterns identified through latent class analysis.