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Background: Although their benefits are controversial, artificial nutrition and hydration are often administered as a form of basic care to terminally ill patients. An important reason for this may be that these treatments have strong emotional and psychological meanings.
Aims: In the present article we investigated the opinions of Italian physicians and nurses on the administration of artificial nutrition and hydration to terminally ill patients with advanced dementia. We also investigated the antecedents of these opinions, considering feelings and thoughts related to death, ethical issues and training in palliative care.
Method: A questionnaire was administered to Italian physicians (n=288) and nurses (n=763). We analyzed the percentages of agreement with the administration of artificial nutrition and hydration and, using multivariate logistic regressions, the possible antecedents of these opinions.
Results: Agreement with the provision of artificial hydration was higher (73%) than for artificial nutrition (48%), suggesting that artificial hydration may be seen as a form of basic care. Agreement with their administration was generally lower among professionals in northern Italy working in geriatrics wards who had received training in palliative care. We also found that death-related feelings and thoughts and ethical issues played a different part for physicians and nurses.
Conclusions: Our findings suggest that opinions concerning artificial nutrition and hydration not only derive from scientific background, but also relate to cultural, ethical, and psychological issues. Our results also reveal important differences between physicians' and nurses' opinions, providing useful information for interpreting and overcoming obstacles to the effective cooperation between these professionals.
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http://dx.doi.org/10.1089/jpm.2013.0616 | DOI Listing |
Food Chem
August 2025
College of Food Science and Engineering, Qingdao Agricultural University, Qingdao 266109, China. Electronic address:
MXene, a family of two-dimensional transition metal carbides/nitrides, has attracted significant attention in food safety due to its exceptional properties that enable the design of highly efficient sensors. Consequently, a growing consensus in the scientific community highlights the critical role of comprehensive assessments in advancing MXene-based intelligent systems for on-site food quality evaluation. This review covers the advances of MXene based intelligent sensors in fundamental properties, synthesis strategies via various recognition principles and signal output modes, which encompasses multiple areas of food monitoring.
View Article and Find Full Text PDFFront Rehabil Sci
August 2025
Dipartimento Salute Mentale, UOC TSMREE, Asl Roma 3, Rome, Italy.
The Home Artificial Nutrition Unit (HANU) deals with both dysphagic patients receiving enteral and parenteral nutrition and patients who can eat orally with restrictions. In the Lazio Region, the HANU prescribes water gels and thickeners, supplied by the National Health Service (NHS), for safe hydration. Before the employment of a Speech and Language Pathologist (SLP) in the HANU (January 2023), prescriptions were standardized, regardless of the swallowing impairment severity: four jars of thickeners per patient/month and six water gels daily.
View Article and Find Full Text PDFJ Nutr
September 2025
Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, USA; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston,
Food is Medicine (FIM) initiatives are food-based nutrition interventions to prevent or manage chronic disease and improve overall health. It is increasingly embraced across healthcare systems, policy makers, and researchers as a promising strategy to address diet-related chronic diseases. Despite this enthusiasm, questions have been raised about whether FIM is overhyped given the still limited evidence.
View Article and Find Full Text PDFPLoS One
September 2025
Facultad de Medicina, Universidad de Colima, Colima, México.
Uncontrolled hypertension (HTN) increases the risk of adverse health events. This study aimed to identify key predictors of uncontrolled HTN in 1,308 Mexican adults with a prior diagnosis of HTN who were undergoing pharmacological treatment. We utilized data from the 2022 National Health and Nutrition Survey and applied data-driven algorithms within an artificial intelligence framework to enhance predictive accuracy and interpretability.
View Article and Find Full Text PDFCancer Immunol Immunother
September 2025
Center for Food and Nutritional Genomics, Kyungpook National University, Daegu, 41566, Republic of Korea.
Although checkpoint immunotherapy has primarily focused on CD8⁺ T cells, emerging evidence highlights an important role for cytotoxic CD4⁺ T cells in mediating therapeutic responses. However, research on the functional properties of cytotoxic CD4⁺ T cells in the context of immunotherapy is still at an early stage and remains insufficiently defined. Utilizing single-cell RNA-sequencing datasets obtained from metastatic melanoma patients treated with checkpoint inhibitors targeting PD-1 and/or CTLA-4, we performed transcriptomic profiling of conventional CD4⁺ T cells, excluding proliferative and regulatory (FOXP3⁺) subsets, and compared responders and non-responders as distinct groups.
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